|
Body composition
|
PEPCK-C+/+
|
(n)
|
PEPCK-C-/-
|
(n)
|
|---|
|
% Water
|
80.3 ± 0.30
|
3
|
79.26 ± 0.22
|
3
|
|
% Fat
|
3.48 ± 0.36
|
3
|
1.85 ± 0.57
|
3
|
|
% Lean Mass
|
16.42 ± 0.63
|
3
|
18.88 ± 0.78
|
3
|
|
Metabolites in liver
| | | | |
|
Triglyceride (μmoles/g)
|
4.17 ± 1.00
|
5
|
9.58 ± 1.75
|
5
|
|
Lactate (μmoles/g)
|
0.19 ± 0.02
|
3
|
0.37 ± 0.09
|
3
|
|
Malate (μmoles/g)
|
0.24 ± 0.05
|
3
|
2.84 ± 1.58
|
3
|
|
Metabolites in plasma
| | | | |
|
Triglyceride (mg/dl)
|
23.7 ± 6.3
|
3
|
36.3 ± 21.5
|
2
|
|
Ammonia (μmoles/ml)
|
0.14 ± 0.02
|
5
|
0.45 ± 0.28
|
4
|
|
BUN (mg/dl)
|
29.0 ± 7.0
|
2
|
65.5 ± 28.5
|
2
|
|
Lactate (μmoles/ml)
|
0.28 ± 0.13
|
3
|
0.72 ± 0.47
|
3
|
|
β-Hydoxybutyrate (μmoles/ml)
|
5.83 ± 0.21
|
3
|
17.95 ± 0.70
|
3
|
- The values are expressed as the mean ± S.E. for the number of animals shown in parenthesis
