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Table 4 Results of the association test of each SNP against the phenotypic variation residual from the regression of covariates in Table 3. Results significant at alpha ≤ 0.05 are indicated in bold. Also shown are the FDR corrected p-value, the degrees of freedom in the regression model, the regression coefficient indicating the size of the effect of the minor allele, and the minimum effect size for 80% power of detection, relative to the standard deviation.

From: Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction

SNP Gene p-value FDR degf coeff power SNP type
rs936960 LIPC 0.7354 0.8011 47 0.351 2.08 intron 1
rs417344 LIPC 0.1322 0.5433 48 1.175 1.57 ~5.5 kb upstream from LIPC
rs6083 LIPC 0.6944 0.8011 37 -0.226 1.25 S215N
rs295 LPL 0.5519 0.7843 44 -0.526 1.49 intron 6
rs328 LPL 0.1973 0.5744 51 -1.330 1.76 exon 9, *474S
rs10422283 LIPE 0.1610 0.5433 41 0.916 1.24 intron 1
rs1556478 LIPA 0.7417 0.8011 33 0.228 1.29 intron 5
rs6586179 LIPA 0.2575 0.6321 43 -1.189 2.08 exon 1, R23G
rs4245232 LIPG 0.1561 0.5433 43 0.906 1.50 ~1.5 kb upstream
rs814628 LIPF 0.0002 0.0059 43 -3.658 1.86 exon 4, Ala161>Thr
rs2287754 GYS1 0.6950 0.8011 33 -0.324 1.51 5' UTR
rs1478290 GYS2 0.4504 0.7843 57 -0.381 1.13 ~3.5 Kb upstream
rs1871143 GYS2 0.5236 0.7843 38 -0.381 1.31 intron 11
rs2306179 GYS2 0.0068 0.0610 42 -1.717 1.40 intron 5
rs4688046 GSK3B 0.5148 0.7843 42 -0.382 1.37 intron 3
rs334555 GSK3B 0.4553 0.7843 41 0.925 2.09 intron 1
rs711752 CETP 0.2127 0.5744 44 0.677 1.13 intron 1
rs3764261 CETP 0.6900 0.8011 39 0.263 1.36 ~2.6 kb upstream
rs5880 CETP 0.0782 0.4220 42 2.769 2.71 P390A
rs1532624 CETP 0.5299 0.7843 49 0.339 1.12 intron 7
rs5883 CETP 0.0018 0.0237 54 -2.854 1.94 exon 9, synonymous
rs5070 APOA1 0.4406 0.7843 39 -0.454 1.41 Intron
rs4520 APOC3 0.4275 0.7843 36 -0.497 1.32 G34G
rs2071521 APOC3 0.9176 0.9176 43 -0.053 1.13 Upstream
rs694066 GAL 0.0231 0.1557 54 2.105 2.22 intron 1
rs1468271 NPY 0.7401 0.8011 46 -0.378 2.43 intron 1
rs26312 GHRL 0.7832 0.8133 61 0.233 1.50 ~1 kb upstream