Bio F1B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism

Table 5 High-density lipoprotein (HDL) lipid concentrations for F₁B and Golden Syrian (GS) hamsters

HDL	Diet	Animal Strain		Statistical Analysis
(mmol/L)		F1B	GS	Interaction	P value
Cholesterol	FO	1.55 ± 0.30	1.46 ± 0.08	S	P = 0.0163
	MUFA	2.22 ± 0.17	1.46 ± 0.11
	N6:N3	1.73 ± 0.07	1.53 ± 0.19
Triglycerides	FO	3.23 ± 1.54	0.69 ± 0.12	D	P = 0.0035
	MUFA	0.06 ± 0.01	0.06 ± 0.03
	N6:N3	0.33 ± 0.12	0.20 ± 0.06
Free Cholesterol	FO	1.24 ± 0.33	0.69 ± 0.07	D	P = 0.0102
	MUFA	0.65 ± 0.22	0.41 ± 0.02	S	P = 0.0120
	N6:N3	0.59 ± 0.20	0.32 ± 0.05
Cholesterol Esters	FO	0.56 ± 0.15	0.94 ± 0.20	D × S	P = 0.0129
	MUFA	1.77 ± 0.25	1.04 ± 0.11	D	P = 0.0035
	N6:N3	1.14 ± 0.20	1.21 ± 0.15

Hamsters were fed the fish oil (FO), monounsaturated fatty acid rich (MUFA) or N6:N3 diets for 4 weeks. Lipids were analysed as described under materials and methods section. Values are means SEM, (n = 6 for F1B, n = 6 for GS). Groups were compared by two-way ANOVA, p = 0.05. D, S represents diet and strain respectively.

ISSN: 1743-7075