| |
Week 0
|
Week 12
|
Week 24
|
Week 0 to 24
|
Between Groups
|
Between Groups Adjusted*
|
|---|
| |
mean ± sd
|
mean ± sd
|
mean ± sd
|
mean change
|
p value
|
p value
|
|
LGID
|
n = 29
|
n = 29
|
n = 29
| | | |
|
Hemoglobin A1c, %
|
8.3 ± 1.9
|
7.5 ± 1.7
|
7.8 ± 2.1
|
-0.5
|
0.03
|
0.06
|
|
Fasting glucose, mg/dL
|
166.8 ± 63.7
|
140.7 ± 39.9
|
150.8 ± 47.4
|
-16.0**
|
0.67
|
0.76
|
|
Fasting insulin, μU/mL
|
14.8 ± 6.9
|
13.9 ± 9.9
|
12.6 ± 6.5
|
-2.2**
|
0.10
|
0.84
|
|
Body mass index, kg/m2
|
37.9 ± 6.0
|
36.5 ± 5.7
|
35.2 ± 6.1
|
-2.7**
|
0.05
|
0.10
|
|
Body weight, kg
|
105.2 ± 19.8
|
101.0 ± 16.9
|
98.3 ± 20.3
|
-6.9**
|
0.008
|
0.01
|
|
LCKD
|
n = 21
|
n = 21
|
n = 21
| | | |
|
Hemoglobin A1c, %
|
8.8 ± 1.8
|
7.2 ± 1.2
|
7.3 ± 1.5
|
-1.5**
| | |
|
Fasting glucose, mg/dL
|
178.1 ± 72.9
|
156.4 ± 50.7
|
158.2 ± 50.0
|
-19.9**
| | |
|
Fasting insulin, uU/mL
|
20.4 ± 9.3
|
14.3 ± 8.3
|
14.4 ± 6.9
|
-6.0**
| | |
|
Body mass index, kg/m2
|
37.8 ± 6.7
|
34.4 ± 5.6
|
33.9 ± 5.8
|
-3.9**
| | |
|
Body weight, kg
|
108.4 ± 20.5
|
100.1 ± 17.8
|
97.3 ± 17.6
|
-11.1**
| | |
- LGID = low-glycemic, reduced-calorie diet; LCKD = low-carbohydrate, ketogenic diet
- * Adjusted for baseline values.
- ** p < 0.05 for within-group change from Baseline to Week 24.
