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Table 2 Threshold determination to define hyperhomocysteinemia

From: Plasma homocysteine in adolescents depends on the interaction between methylenetetrahydrofolate reductase genotype, lipids and folate: a seroepidemiological study

Hyperhomocysteinemia P50 P75 P90 P95 Hcy ≥ 12 Hcy ≥ 15
Threshold [Hcy]/μM 4.30 5.93 8.23 10.41 12.00 15.00
Number of cases 157 78 32 15 8 4
Prevalence % 49.53 24.61 10.1 4.73 2.52 1.26
95% CI 43.99-55.06 19.84-29.37 6.78-13.41 2.38-7.08 0.79-4.26 0.03-2.50
  1. P: percentile