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Table 5 Risk factor accumulation: genotype, folate and HDL-cholesterol

From: Plasma homocysteine in adolescents depends on the interaction between methylenetetrahydrofolate reductase genotype, lipids and folate: a seroepidemiological study

Genotype Folate cHDL % Hyperhomocysteinemia
CC Normal Normal 10.7
   Low levels** 18.2
  Low levels* Normal 31.8
   Low levels** 0.0
CT Normal Normal 20.2
   Low levels** 36.8
  Low levels* Normal 29.2
   Low levels** 66.7
TT Normal Normal 38.1
   Low levels** 33.3
  Low levels* Normal 55.6
   Low levels** 100.0
  1. HDL: High Density Lipoproteins
  2. MTHFR: methylenetetrahydrofolate reductase
  3. C: Cytosine; T:Thymine
  4. *<5.3 nmol/l
  5. **<35 mg/dl