Figure 2

BALF cytokine levels. Concentration of protein determined by ELISA in immunized and challenged mice 24 h after last intranasal allergen challenge (n = 8/group). (A) IL-4 levels were significantly augmented in all treated groups compared to non-treated group. (B) IL-5 levels were significantly augmented in groups treated with 50 and 500 ug of VA every second day compared to non-treated group. However, levels in group of mice treated with 2,500 ug every second day, were reduced compared to previous treated groups. There was not significant difference between 2,500 group and non-treated group. (C) IFN-γ in airways was not modified in treated mice. (D) Total IgE content in airways was also significantly increased after treatment with RA in all groups compared to non-treated mice. Data are given as mean ± SEM, *P < 0.05 vs. non-treated group.