Acute and timing effects of beta-hydroxy-beta-methylbutyrate (HMB) on indirect markers of skeletal muscle damage

Nutrition & Metabolism

Table 2 Values for CK, MVC, and VAS for the three supplement groups

Variables		0	8 hrs	24 hrs	48 hrs	72 hrs
MVC Knee Extensors	Control	216 ± 10	178 ± 29*	193 ± 17	191 ± 16	180 ± 22*
(N)	Pre	224 ± 15	170 ± 28*	188 ± 17	206 ± 16	165 ± 22*
	Post	231 ± 15	171 ± 28*	210 ± 16	208 ± 15	215 ± 23
MVC Knee Flexors	Control	118 ± 7	92 ± 11	82 ± 6	80 ± 8	76 ± 8
(N)	Pre	127 ± 10	92 ± 16	91 ± 9	97 ± 11	79 ± 12*
	Post	127 ± 12	88 ± 13	92 ± 11*	71 ± 12*	85 ± 14*
VAS Quadriceps	Control	0.0 ± 0.0	2.0 ± 0.4	2 ± 0.4	2.6 ± 1.4*	1.0 ± 0.4
(cm)	Pre	0.0 ± 0.0	0.7 ± 0.5	1.9 ± 1.0*	1.5 ± 1.0	0.9 ± 1.0
	Post	0.0 ± 0.0	1.0 ± 0.3	2.0 ± 1.0	3.0 ± 1.0*	2.6 ± 1.0*
VAS Hamstrings	Control	0.0 ± 0.0	1.1 ± 0.3	2.1 ± 0.5	4.2 ± 0.6*	2.4 ± 0.5*
(cm)	Pre	0.0 ± 0.0	0.7 ± 0.7	2.3 ± 0.7	3.4 ± 0.8*	2.4 ± 0.7
	Post	0.0 ± 0.0	1.2 ± 0.5	2.2 ± 0.7	4.4 ± 0.9*	4.1 ± 0.8*
CK	Control	165 ± 36	398 ± 95	623 ± 140	1032 ± 141*	801 ± 204
(U/L)	Pre	201 ± 51	382 ± 135	551 ± 135	853 ± 396	1098 ± 289*
	Post	199 ± 51	430 ± 134	759 ± 199	1531 ± 937*	937 ± 289*
LDH	Control	113 ± 7	125 ± 10	131 ± 18	186 ± 29	372 ± 78*
(U/L)	Pre	144 ± 10	154 ± 23	134 ± 25	159 ± 41	224 ± 110
	Post	124 ± 10	129 ± 22	129 ± 26	219 ± 41	419 ± 111*

Values are means ± standard deviation.
* p < 0.05, significantly different from 0 time point
Pre, received supplement before exercise and placebo after; Post, received supplement after exercise and placebo before exercise; Control, received placebo before and after exercise; CK, creatine kinase; MVC, maximal voluntary contraction; N, newtons; VAS, visual analogue scale.

ISSN: 1743-7075