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Table 5 Effect of maternal dietary -linolenic acid (ALA) compared to n-3 LC-PUFA (EPA+DHA) on the polyunsaturated fatty acid and DMA composition of phosphatidylethanolamine (PE) and phosphatidylserine (PS) in brain glial cells of pups (g/100 g total fatty acids).

From: Differential effect of maternal diet supplementation with α-Linolenic acid or n-3 long-chain polyunsaturated fatty acids on glial cell phosphatidylethanolamine and phosphatidylserine fatty acid profile in neonate rat brains

  Phosphatidylethanolamine (PE) Phosphaptidylserine (PS)
  Experimental group Experimental group
  ALA n-3 LC-PUFA   ALA n-3 LC-PUFA  
  Mean ± SD P values Mean ± SD P values
C18:2n-6 1.04 ± 0.12 1.17 ± 0.07 n.s. 0.46 ± 0.05 0.55 ± 0.18 n.s.
C20:2n-6 0.35 ± 0.03 0.32 ± 0.10 n.s. 0.32 ± 0.03 0.32 ± 0.08 n.s.
C20:3n-6 0.73 ± 0.01 0.93 ± 0.02 0.0018 0.77 ± 0.11 0.77 ± 0.09 n.s.
C20:4n-6 20.16 ± 0.84 17.34 ± 0.45 < 0.0001 7.93 ± 0.32 7.38 ± 0.19 n.s.
C22:4n-6 7.17 ± 0.49 6.99 ± 0.27 n.s. 6.53 ± 0.30 5.94 ± 0.71 n.s.
C22:5n-6 2.71 ± 0.21 1.64 ± 0.07 0.0003 4.07 ± 0.48 2.14 ± 0.29 < 0.0001
C18:3n-3 0.11 ± 0.07 0.12 ± 0.05 n.s. 0.16 ± 0.02 0.19 ± 0.03 n.s.
C20:5n-3 0.12 ± 0.07 0.11 ± 0.05 n.s. 0.18 ± 0.03 0.11 ± 0.05 n.s.
C22:5n-3 0.65 ± 0.02 0.80 ± 0.06 n.s. 1.07 ± 0.10 0.93 ± 0.16 n.s.
C22:6n-3 22.89 ± 0.60 27.83 ± 0.72 0.0001 26.15 ± 0.73 30.12 ± 2.27 0.0009
DMA 8.29 ± 0.34 9.40 ± 0.79 0.0155 2.18 ± 0.49 1.57 ± 0.52 n.s.
  1. Data obtained from four pools of 6 brains excised from rat pups at 2 weeks of age.