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Table 5 Effect of maternal dietary -linolenic acid (ALA) compared to n-3 LC-PUFA (EPA+DHA) on the polyunsaturated fatty acid and DMA composition of phosphatidylethanolamine (PE) and phosphatidylserine (PS) in brain glial cells of pups (g/100 g total fatty acids).

From: Differential effect of maternal diet supplementation with α-Linolenic acid or n-3 long-chain polyunsaturated fatty acids on glial cell phosphatidylethanolamine and phosphatidylserine fatty acid profile in neonate rat brains

 

Phosphatidylethanolamine (PE)

Phosphaptidylserine (PS)

 

Experimental group

Experimental group

 

ALA

n-3 LC-PUFA

 

ALA

n-3 LC-PUFA

 
 

Mean ± SD

P values

Mean ± SD

P values

C18:2n-6

1.04 ± 0.12

1.17 ± 0.07

n.s.

0.46 ± 0.05

0.55 ± 0.18

n.s.

C20:2n-6

0.35 ± 0.03

0.32 ± 0.10

n.s.

0.32 ± 0.03

0.32 ± 0.08

n.s.

C20:3n-6

0.73 ± 0.01

0.93 ± 0.02

0.0018

0.77 ± 0.11

0.77 ± 0.09

n.s.

C20:4n-6

20.16 ± 0.84

17.34 ± 0.45

< 0.0001

7.93 ± 0.32

7.38 ± 0.19

n.s.

C22:4n-6

7.17 ± 0.49

6.99 ± 0.27

n.s.

6.53 ± 0.30

5.94 ± 0.71

n.s.

C22:5n-6

2.71 ± 0.21

1.64 ± 0.07

0.0003

4.07 ± 0.48

2.14 ± 0.29

< 0.0001

C18:3n-3

0.11 ± 0.07

0.12 ± 0.05

n.s.

0.16 ± 0.02

0.19 ± 0.03

n.s.

C20:5n-3

0.12 ± 0.07

0.11 ± 0.05

n.s.

0.18 ± 0.03

0.11 ± 0.05

n.s.

C22:5n-3

0.65 ± 0.02

0.80 ± 0.06

n.s.

1.07 ± 0.10

0.93 ± 0.16

n.s.

C22:6n-3

22.89 ± 0.60

27.83 ± 0.72

0.0001

26.15 ± 0.73

30.12 ± 2.27

0.0009

DMA

8.29 ± 0.34

9.40 ± 0.79

0.0155

2.18 ± 0.49

1.57 ± 0.52

n.s.

  1. Data obtained from four pools of 6 brains excised from rat pups at 2 weeks of age.