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Table 7 Blood glucose and blood pressure dynamics for 13 male Nile rats fed chow (#5020) divided at 22 wks into early-onset and late-onset groups followed for 21 wks (Expt 9)

From: Nutritional correlates and dynamics of diabetes in the Nile rat (Arvicanthis niloticus): a novel model for diet-induced type 2 diabetes and the metabolic syndrome

 

Groups

 

Early-onset

Late-onset

Fasting blood glucose (mg/dL)

  

   22 wk of age

271 ± 34

77 ± 34*

   27 wk of age

406 ± 73

137 ± 92*

   34 wk of age

371 ± 124

71 ± 20*

   40 wk of age

339 ± 43

211 ± 120*

   43 wk of age

425 ± 33

288 ± 196*

Systolic blood pressure (mmHg)

  

   27 wk of age

128 ± 8

123 ± 10

   34 wk of age

156 ± 8

134 ± 6*

   40 wk of age

171 ± 13

137 ± 7*

   43 wk of age

164 ± 6

158 ± 7

Body weight (g)

  

   Initial (age: 8 wks)

83 ± 5

76 ± 4

   22 wk of age

115 ± 13

117 ± 12

   27 wk of age

116 ± 12

125 ± 10

   34 wk of age

113 ± 18

127 ± 11

   40 wk of age

114 ± 14

125 ± 10

   43 wk of age

109 ± 12

123 ± 11

Plasma (43 wk of age)

  

   Insulin (ng/mL)

0.9 ± 0.9

3.0 ± 2.0*

   TC (mg/dL)

413 ± 302

139 ± 98*

   TG (mg/dL)

1472 ± 1282

253 ± 245*

  1. Values are mean ± SD (early-onset n = 3, late-onset n = 10)
  2. * Significantly different (P < 0.05)