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Table 7 Blood glucose and blood pressure dynamics for 13 male Nile rats fed chow (#5020) divided at 22 wks into early-onset and late-onset groups followed for 21 wks (Expt 9)

From: Nutritional correlates and dynamics of diabetes in the Nile rat (Arvicanthis niloticus): a novel model for diet-induced type 2 diabetes and the metabolic syndrome

  Groups
  Early-onset Late-onset
Fasting blood glucose (mg/dL)   
   22 wk of age 271 ± 34 77 ± 34*
   27 wk of age 406 ± 73 137 ± 92*
   34 wk of age 371 ± 124 71 ± 20*
   40 wk of age 339 ± 43 211 ± 120*
   43 wk of age 425 ± 33 288 ± 196*
Systolic blood pressure (mmHg)   
   27 wk of age 128 ± 8 123 ± 10
   34 wk of age 156 ± 8 134 ± 6*
   40 wk of age 171 ± 13 137 ± 7*
   43 wk of age 164 ± 6 158 ± 7
Body weight (g)   
   Initial (age: 8 wks) 83 ± 5 76 ± 4
   22 wk of age 115 ± 13 117 ± 12
   27 wk of age 116 ± 12 125 ± 10
   34 wk of age 113 ± 18 127 ± 11
   40 wk of age 114 ± 14 125 ± 10
   43 wk of age 109 ± 12 123 ± 11
Plasma (43 wk of age)   
   Insulin (ng/mL) 0.9 ± 0.9 3.0 ± 2.0*
   TC (mg/dL) 413 ± 302 139 ± 98*
   TG (mg/dL) 1472 ± 1282 253 ± 245*
  1. Values are mean ± SD (early-onset n = 3, late-onset n = 10)
  2. * Significantly different (P < 0.05)