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Table 5 mRNA levels of proinflammatory gene expression from PBMC with respect to tertiles (T)a of energy-adjusted fruit and vegetable consumption, fiber from fruit and vegetable consumption and dietary TAC (n = 120)

From: Fruit and vegetable consumption and proinflammatory gene expression from peripheral blood mononuclear cells in young adults: a translational study

Proinflammatory gene expression (arbitrary units)

Energy-adj. fruit and vegetable consumption

P for trend

 

T1

(<384 g/d)

T2

(384-660 g/d)

T3

(>660 g/d)

 

ICAM1

2.03 ± 0.43

1.81 ± 0.40

1.75 ± 0.50

0.002

IL1R1

2.10 ± 0.58

1.95 ± 0.53

1.80 ± 0.56

0.003

IL6

2.02 ± 0.52

1.94 ± 0.61

1.75 ± 0.79

0.005

TNFα

1.96 ± 0.53

1.81 ± 0.49

1.68 ± 0.65

0.025

NFκB1(p50)

6.28 ± 4.81

5.08 ± 3.30

3.60 ± 1.90

0.004

RELA (p65)

3.49 ± 2.70

2.48 ± 1.85

2.17 ± 2.10

0.055

 

Energy adj. fiber from fruits and vegetables

P for trend

 

T1

(<6.0 g/d)

T2

(6.0-19.5 g/d)

T3

(>19.5 g/d)

 

ICAM1

1.94 ± 0.38

1.87 ± 0.47

1.77 ± 0.47

0.007

IL1R1

1.99 ± 0.54

1.95 ± 0.59

1.88 ± 0.57

0.263

IL6

2.0 ± 0.52

1.90 ± 0.74

1.81 ± 0.63

0.156

TNFα

1.89 ± 0.49

1.81 ± 0.64

1.74 ± 0.55

0.012

NFκB1(p50)

5.92 ± 2.36

5.30 ± 3.51

3.67 ± 2.53

0.011

RELA (p65)

3.05 ± 2.36

2.94 ± 2.31

2.17 ± 1.62

0.104

 

Energy-adjusted dietary TAC

P for trend

 

T1

(<5.3 mmol/d)

T2

(5.3-11.8 mmol/d)

T3

(>11.8 mmol/d)

 

ICAM1

1.91 ± 0.42

1.87 ± 0.47

1.79 ± 0.48

0.038

IL1R1

1.99 ± 0.57

1.95 ± 0.54

1.88 ± 0.59

0.020

IL6

1.97 ± 0.67

1.92 ± 0.65

1.85 ± 0.63

0.042

TNFα

1.89 ± 0.60

1.81 ± 0.51

1.75 ± 0.59

0.031

NFκB1(p50)

5.65 ± 4.51

5.21 ± 3.83

4.05 ± 2.17

0.035

RELA (p65)

3.05 ± 2.53

2.85 ± 1.95

2.30 ± 1.85

0.088

  1. a Tertile 1, n = 39; Tertile 2, n = 42; Tertile 3, n = 39.
  2. P for trend from linear regression model, adjusting for gender, age, BMI, energy intake, physical activity, smoking, systolic blood pressure and non-esterified fatty acid concentration. TAC, total antioxidant capacity; ICAM1, intercellular adhesion molecule-1; IL1R1, interleukin-1 receptor-1; IL6, interleukin-6; NFκB1, nuclear factor-nuclear-kappa-B (p50); PBMC, peripheral blood mononuclear cells; RELA, nuclear factor-nuclear-kappa-B (p65); TNFα, tumor necrosis factor-alpha.