Skip to main content

Advertisement

Table 5 mRNA levels of proinflammatory gene expression from PBMC with respect to tertiles (T)a of energy-adjusted fruit and vegetable consumption, fiber from fruit and vegetable consumption and dietary TAC (n = 120)

From: Fruit and vegetable consumption and proinflammatory gene expression from peripheral blood mononuclear cells in young adults: a translational study

Proinflammatory gene expression (arbitrary units) Energy-adj. fruit and vegetable consumption P for trend
  T1
(<384 g/d)
T2
(384-660 g/d)
T3
(>660 g/d)
 
ICAM1 2.03 ± 0.43 1.81 ± 0.40 1.75 ± 0.50 0.002
IL1R1 2.10 ± 0.58 1.95 ± 0.53 1.80 ± 0.56 0.003
IL6 2.02 ± 0.52 1.94 ± 0.61 1.75 ± 0.79 0.005
TNFα 1.96 ± 0.53 1.81 ± 0.49 1.68 ± 0.65 0.025
NFκB1(p50) 6.28 ± 4.81 5.08 ± 3.30 3.60 ± 1.90 0.004
RELA (p65) 3.49 ± 2.70 2.48 ± 1.85 2.17 ± 2.10 0.055
  Energy adj. fiber from fruits and vegetables P for trend
  T1
(<6.0 g/d)
T2
(6.0-19.5 g/d)
T3
(>19.5 g/d)
 
ICAM1 1.94 ± 0.38 1.87 ± 0.47 1.77 ± 0.47 0.007
IL1R1 1.99 ± 0.54 1.95 ± 0.59 1.88 ± 0.57 0.263
IL6 2.0 ± 0.52 1.90 ± 0.74 1.81 ± 0.63 0.156
TNFα 1.89 ± 0.49 1.81 ± 0.64 1.74 ± 0.55 0.012
NFκB1(p50) 5.92 ± 2.36 5.30 ± 3.51 3.67 ± 2.53 0.011
RELA (p65) 3.05 ± 2.36 2.94 ± 2.31 2.17 ± 1.62 0.104
  Energy-adjusted dietary TAC P for trend
  T1
(<5.3 mmol/d)
T2
(5.3-11.8 mmol/d)
T3
(>11.8 mmol/d)
 
ICAM1 1.91 ± 0.42 1.87 ± 0.47 1.79 ± 0.48 0.038
IL1R1 1.99 ± 0.57 1.95 ± 0.54 1.88 ± 0.59 0.020
IL6 1.97 ± 0.67 1.92 ± 0.65 1.85 ± 0.63 0.042
TNFα 1.89 ± 0.60 1.81 ± 0.51 1.75 ± 0.59 0.031
NFκB1(p50) 5.65 ± 4.51 5.21 ± 3.83 4.05 ± 2.17 0.035
RELA (p65) 3.05 ± 2.53 2.85 ± 1.95 2.30 ± 1.85 0.088
  1. a Tertile 1, n = 39; Tertile 2, n = 42; Tertile 3, n = 39.
  2. P for trend from linear regression model, adjusting for gender, age, BMI, energy intake, physical activity, smoking, systolic blood pressure and non-esterified fatty acid concentration. TAC, total antioxidant capacity; ICAM1, intercellular adhesion molecule-1; IL1R1, interleukin-1 receptor-1; IL6, interleukin-6; NFκB1, nuclear factor-nuclear-kappa-B (p50); PBMC, peripheral blood mononuclear cells; RELA, nuclear factor-nuclear-kappa-B (p65); TNFα, tumor necrosis factor-alpha.