Table 1 Baseline clinical characteristics.
From: Plasma bile acids are not associated with energy metabolism in humans
| Â | colesevelam HCl study | liver cirrhosis study | ||
|---|---|---|---|---|
| Â | T2DM | controls | cirrhosis | controls |
| Â | n = 12 | n = 12 | n = 46 | n = 20 |
Age (years) | 52.5 ± 1.3 | 49.0 ± 1.4 | 48.1 ± 1.3 | 46.9 ± 2.5 |
Gender (male/female) | 12/0 | 12/0 | 26/20 | 12/8 |
BMI (kg/m2) | 31.1 ± 0.8 | 29.4 ± 1.1 | 23.0 ± 0.4 | 23.6 ± 0.9 |
Cholesterol (mM) | 5.0 ± 0.3 | 4.4 ± 0.2 | 4.7 ± 0.2 | 4.9 ± 0.3 |
Triglycerides (mM) | 3.0 ± 0.4 | 1.4 ± 0.2# | 1.0 ± 0.1 | 1.1 ± 0.1 |
Glucose (mM) | 9.4 ± 0.7 | 5.0 ± 0.2# | 6.2 ± 0.2 | 4.6 ± 0.1‡ |
HOMA-IR | 6.60 ± 0.98 | 1.97 ± 1.04# | 4.58 ± 0.42 | 1.80 ± 0.26‡ |
AST (U/l) | 21 ± 2 | 19 ± 1 | 37 ± 3 | 15 ± 1‡ |
ALT (U/l) | 25 ± 2 | 24 ± 3 | 32 ± 3 | 16 ± 1‡ |
γ-GT (U/l) | n.d. | n.d. | 89 ± 10 | 17 ± 2‡ |