Table 2 Clinical and biochemical characteristics at baseline and after supplementation1,2
MCT intake > 7 g/d (n = 21) | MCT intake ≤ 7 g/d (n = 22) | Pb | |||||||
|---|---|---|---|---|---|---|---|---|---|
wk 0 | wk 12 | wk 12 - 0 | P a | wk 0 | wk12 | wk 12 - 0 | P a | ||
Age (years) | 67.3 ± 9.3 | 66.3 ± 7.2 | 0.512 | ||||||
Weight (kg) | 95.7 ± 21.2 | 95.3 ± 21.7 | -0.35 ± 1.92 | 0.641 | 87.7 ± 11.6 | 88.3 ± 11.7 | 0.54 ± 1.76 | 0.118 | 0.177 |
BMI (kg/m2) | 34.35 ± 6.84 | 34.23 ± 7.08 | -0.12 ± 0.70 | 0.681 | 31.69 ± 4.05 | 31.89 ± 4.10 | 0.20 ± 0.61 | 0.092 | 0.174 |
WC (cm) | 112.5 ± 12.5 | 110.7 ± 12.9 | -1.81 ± 2.69 | 0.005 | 106.4 ± 6.6 | 106.7 ± 7.0 | 0.32 ± 3.03 | 1.000 | 0.027 |
WHtR | 0.676 ± 0.076 | 0.665 ± 0.079 | -0.010 ± 0.016 | 0.008 | 0.640 ± 0.045 | 0.642 ± 0.049 | 0.002 ± 0.018 | 0.920 | 0.018 |
SBP (mmHg) | 138.6 ± 18.4 | 137.9 ± 12.0 | -0.7 ± 13.2 | 0.792 | 148.4 ± 18.6 | 142.0 ± 17.2 | -6.4 ± 15.4 | 0.069 | 0.249 |
DBP (mmHg) | 84.8 ± 11.7 | 84.1 ± 7.7 | -0.7 ± 10.3 | 0.707 | 87.7 ± 8.7 | 85.2 ± 8.7 | -2.5 ± 9.2 | 0.170 | 0.612 |
Fasting TG (mg/dl) | 147.3 ± 92.0 | 181.6 ± 122.7 | 34.2 ± 72.6 | 0.021 | 166.5 ± 113.3 | 216.6 ± 177.1 | 50.1 ± 108.1 | 0.022 | 0.990 |
TC (mg/dl) | 209.5 ± 41.0 | 214.0 ± 41.6 | 4.52 ± 18.60 | 0.177 | 217.7 ± 37.9 | 225.4 ± 42.7 | 7.68 ± 23.04 | 0.058 | 0.527 |
LDL-C (mg/dl) | 128.8 ± 34.9 | 130.7 ± 32.3 | 1.95 ± 16.59 | 0.357 | 136.4 ± 34.9 | 135.6 ± 40.1 | -0.86 ± 22.04 | 0.848 | 0.618 |
HDL-C (mg/dl) | 52.1 ± 10.8 | 49.7 ± 10.6 | -2.39 ± 8.75 | 0.230 | 49.5 ± 9.9 | 51.4 ± 13.9 | 1.88 ± 6.71 | 0.363 | 0.085 |
TC/HDL-C | 4.15 ± 0.98 | 4.50 ± 1.37 | 0.35 ± 0.82 | 0.064 | 4.51 ± 1.01 | 4.65 ± 1.50 | 0.14 ± 0.70 | 0.637 | 0.289 |
Non-HDL-C (mg/dl) | 157.4 ± 40.3 | 164.3 ± 43.5 | 6.91 ± 18.8 | 0.058 | 168.2 ± 35.6 | 174.0 ± 42.8 | 5.80 ± 22.7 | 0.158 | 0.981 |
Fasting glucose (mg/dl) | 127.5 ± 21.8 | 132.0 ± 29.7 | 4.48 ± 19.91 | 0.422 | 124.4 ± 23.9 | 126.5 ± 34.6 | 2.09 ± 18.70 | 0.676 | 0.313 |
Fasting insulin (μU/ml) | 12.6 ± 9.1 | 13.7 ± 11.0 | 1.09 ± 9.33 | 0.509 | 14.4 ± 6.8 | 17.6 ± 25.4 | 3.17 ± 24.16 | 0.299 | 0.177 |
HOMA-Index | 4.14 ± 3.73 | 4.81 ± 5.52 | 0.68 ± 5.21 | 0.639 | 4.46 ± 2.39 | 5.72 ± 9.01 | 1.26 ± 8.68 | 0.306 | 0.234 |
HbA1c (%) | 6.76 ± 0.58 | 6.69 ± 0.78 | -0.067 ± 0.380 | 0.367 | 6.46 ± 0.47 | 6.46 ± 0.53 | 0.004 ± 0.208 | 0.844 | 0.179 |
CRP (mg/l) | 6.17 ± 5.97 | 5.52 ± 4.91 | -0.66 ± 2.77 | 0.140 | 5.80 ± 8.46 | 4.45 ± 4.63 | -1.35 ± 6.76 | 0.274 | 0.961 |
Uric acid (mg/l) | 5.96 ± 1.53 | 6.27 ± 1.52 | 0.31 ± 0.66 | 0.024 | 6.58 ± 1.26 | 6.58 ± 1.04 | 0.00 ± 1.09 | 0.944 | 0.103 |
GGT (U/l) | 43.8 ± 50.1 | 41.2 ± 26.4 | -2.57 ± 27.84 | 0.265 | 43.8 ± 47.6 | 44.2 ± 30.5 | 0.45 ± 20.82 | 0.023 | 0.442 |
ASAT (U/l) | 28.4 ± 10.6 | 28.0 ± 8.3 | -0.43 ± 5.97 | 0.861 | 28.1 ± 11.9 | 27.1 ± 6.5 | -1.00 ± 9.01 | 0.480 | 0.643 |
ALAT (U/l) | 33.5 ± 21.8 | 31.2 ± 14.3 | -2.24 ± 9.96 | 0.650 | 29.2 ± 14.1 | 30.4 ± 13.8 | 1.18 ± 10.77 | 0.166 | 0.607 |
GFR (mL/min/1.73 m2) | 87.9 ± 19.1 | 86.4 ± 22.4 | -1.54 ± 11.28 | 0.433 | 81.7 ± 15.7 | 83.4 ± 14.9 | 1.71 ± 8.60 | 0.095 | 0.290 |
U-Albumin (mg/24 h) | 55.3 ± 199.4 | 19.5 ± 39.9 | -35.8 ± 162.7 | 0.594 | 62.1 ± 225.8 | 60.0 ± 150.1 | -2.1 ± 109.3 | 0.641 | 0.842 |
U-pH (24 h) | 5.81 ± 0.81 | 5.52 ± 0.73 | -0.29 ± 0.70 | 0.062 | 5.80 ± 1.08 | 6.05 ± 1.12 | 0.25 ± 0.88 | 0.176 | 0.032 |
U-Sodium (mmol/24 h) | 212.0 ± 84.6 | 234.5 ± 89.0 | 22.5 ± 78.2 | 0.145 | 208.6 ± 67.6 | 231.0 ± 75.6 | 22.4 ± 72.2 | 0.153 | 1.000 |