Table 3 Insulin, HOMA-IR and Fatty acid composition (%) in serum phospholipids according to FEN1 -10154G>T, FADS2 rs174575, FADS2 rs2727270 and rsFADS 3 1000778C>T

GG (n = 259)

T carrier (n = 308)

CC (n = 471)

G carrier (n = 96)

CC (n = 323)

T carrier (n = 244)

GG (n = 259)

GT+TT (n = 308)

9.1 ± 4.2

8.8 ± 4.3

8.7 ± 3.8

9.7 ± 5.9*

9.3 ± 4.8

8.4 ± 3.3*

8.6 ± 3.6

9.2 ± 4.8

2.11 ± 1.04

2.03 ± 1.12

2.00 ± 0.96

2.28 ± 1.53*

2.17 ± 1.23

1.93 ± 0.83*

1.98 ± 0.91

2.15 ± 1.23

54.724 ± 0.340

53.694 ± 0.339*

54.374 ± 0.265

53.139 ± 0.583

54.487 ± 0.305

53.739 ± 0.389

54.039 ± 5.359

54.288 ± 6.117

0.367 ± 0.014

0.411 ± 0.016

0.392 ± 0.012

0.386 ± 0.026

0.377 ± 0.013

0.410 ± 0.018

0.394 ± 0.264

0.388 ± 0.247

0.595 ± 0.017

0.683 ± 0.056

0.650 ± 0.037

0.604 ± 0.031

0.599 ± 0.016

0.700 ± 0.070

0.599 ± 0.254

0.685 ± 1.019

32.736 ± 0.325

32.206 ± 0.298

32.509 ± 0.247

32.152 ± 0.474

32.666 ± 0.283

32.161 ± 0.348

32.403 ± 4.945

32.493 ± 5.514

19.067 ± 0.204

18.487 ± 0.198*

18.886 ± 0.156

18.092 ± 0.348**

18.892 ± 0.186

18.566 ± 0.223

18.676 ± 3.181

18.826 ± 3.604

11.353 ± 0.134

11.514 ± 0.146

11.352 ± 0.104

11.877 ± 0.297*

11.483 ± 0.134

11.385 ± 0.151

11.574 ± 2.491

11.311 ± 2.282

0.628 ± 0.028

0.733 ± 0.048

0.650 ± 0.025

0.859 ± 0.117

0.656 ± 0.032

0.724 ± 0.052

0.681 ± 0.721

0.689 ± 0.655

6.917 ± 0.101

6.996 ± 0.108

6.903 ± 0.077

7.234 ± 0.225

7.002 ± 0.103

6.903 ± 0.108

7.015 ± 1.869

6.905 ± 1.678

1.729 ± 0.025

1.712 ± 0.027

1.715 ± 0.020

1.744 ± 0.050

1.739 ± 0.024

1.694 ± 0.029

1.755 ± 0.434

1.685 ± 0.445

23.978 ± 0.377

24.046 ± 0.349

23.863 ± 0.278

24.761 ± 0.648

24.073 ± 0.343

23.939 ± 0.385

24.135 ± 5.709

23.897 ± 6.455

19.237 ± 0.297

19.229 ± 0.274

19.082 ± 0.217

19.973 ± 0.528

19.304 ± 0.272

19.138 ± 0.298

19.286 ± 4.365

19.180 ± 5.178

12.062 ± 0.186

12.853 ± 0.181**

12.303 ± 0.139

13.417 ± 0.352**

12.241 ± 0.172

12.824 ± 0.200*

12.394 ± 2.794

12.587 ± 3.410

0.218 ± 0.014

0.233 ± 0.014

0.227 ± 0.012

0.225 ± 0.021

0.223 ± 0.013

0.231 ± 0.017

0.228 ± 0.258

0.225 ± 0.228

0.856 ± 0.104

0.880 ± 0.102

0.864 ± 0.082

0.898 ± 0.161

0.855 ± 0.094

0.888 ± 0.115

0.855 ± 1.790

0.883 ± 1.686

1.504 ± 0.034

1.405 ± 0.031*

1.440 ± 0.024

1.498 ± 0.063*

1.492 ± 0.032

1.394 ± 0.033*

1.458 ± 0.513

1.442 ± 0.580

5.016 ± 0.112

4.323 ± 0.099***

4.690 ± 0.084

4.391 ± 0.162

4.907 ± 0.100

4.285 ± 0.111***

4.806 ± 1.834

4.478 ± 1.748*

0.247 ± 0.020

0.217 ± 0.012

0.230 ± 0.012

0.232 ± 0.024

0.243 ± 0.017

0.214 ± 0.012

0.219 ± 0.191

0.242 ± 0.314

0.190 ± 0.013

0.198 ± 0.012

0.191 ± 0.010

0.209 ± 0.021

0.198 ± 0.012

0.190 ± 0.014

0.182 ± 0.194

0.206 ± 0.227

4.741 ± 0.123

4.818 ± 0.123

4.781 ± 0.097

4.789 ± 0.199

4.769 ± 0.110

4.801 ± 0.141

4.849 ± 2.125

4.717 ± 2.031

0.135 ± 0.006

0.162 ± 0.025

0.153 ± 0.017

0.134 ± 0.009

0.134 ± 0.005

0.170 ± 0.032

0.135 ± 0.096

0.163 ± 0.460

1.158 ± 0.038

1.166 ± 0.042

1.178 ± 0.032

1.085 ± 0.062

1.161 ± 0.034

1.165 ± 0.048

1.197 ± 0.750

1.129 ± 0.602

0.515 ± 0.017

0.546 ± 0.021

0.526 ± 0.015

0.558 ± 0.036

0.523 ± 0.016

0.544 ± 0.024

0.539 ± 0.333

0.525 ± 0.312

2.833 ± 0.088

2.868 ± 0.083

2.837 ± 0.066

2.925 ± 0.146

2.852 ± 0.079

2.851 ± 0.093

2.897 ± 1.458

2.807 ± 1.404

0.019 ± 0.001

0.020 ± 0.002

0.019 ± 0.001

0.018 ± 0.002

0.019 ± 0.001

0.020 ± 0.002

0.019 ± 0.020

0.020 ± 0.028

0.126 ± 0.003

0.112 ± 0.003**

0.120 ± 0.002

0.111 ± 0.004

0.123 ± 0.002

0.113 ± 0.004*

0.119 ± 0.041

0.118 ± 0.059

13.066 ± 0.679

11.460 ± 0.541

12.206 ± 0.469

12.134 ± 1.055

12.527 ± 0.585

11.752 ± 0.626

12.487 ± 10.074

11.907 ± 10.327

0.419 ± 0.010

0.339 ± 0.008***

0.385 ± 0.007

0.327 ± 0.010***

0.404 ± 0.008

0.338 ± 0.010***

0.392 ± 0.157

0.359 ± 0.147**

3.509 ± 0.102

3.192 ± 0.060**

3.383 ± 0.065

3.112 ± 0.099

3.462 ± 0.085

3.172 ± 0.069**

3.387 ± 1.020

3.288 ± 1.618*