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Table 3 Changes in body weight, food intake and plasma leptin concentration in DIO mice.

From: The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters

 

Control

DIO

 

n-3 deficient

Soy oil

n-3 deficient

Soy oil

Soy/fish oil

Fish oil

Body weight (g)

27.69 ± 1.38

27.28 ± 1.14

34.73 ± 2.75 *

32.06 ± 2.16 * ‡

32.86 ± 1.96 * ‡

32.15 ± 1.89 * ‡

Leptin (μg/L)

1.39 ± 0.98

1.54 ± 1.13

8.55 ± 2.39 *

5.95 ± 3.34 *

6.79 ± 3.28 *

4.39 ± 2.09 * ‡

Energy intake (kcal/d/mouse) ¶

23.15 ± 2.59

22.99 ± 1.48

35.17 ± 3.89 *

31.37 ± 2.62 * ‡

32.11 ± 3.17 * ‡

29.54 ± 2.77 * ‡

  1. 3-4 week old C57BL/6J male mice were fed four DIO diets with different fat types and the control diet for 3 months. ¶ Food intake was recorded at 6 weeks. Values are means ± SD, n = 15 in each group. * compared to the control diets, P < 0.05; ‡ compared to the n-3 deficient DIO diet, P < 0.05.