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Table 5 Effect of Zingiber officinale extracts on serum cholestatic markers in CCl4 treated rats

From: Zingiber officinale acts as a nutraceutical agent against liver fibrosis

Parameters Control CCl4 group CCl4 treated with
ethanol extract
CCl4 treated with chloroform extract CCl4 treated with
petroleum ether extract
CCl4 treated with silymarin
GGT 15.78 ± 1.53
(bc)
24.57 ± 3.48
(a)
16.05 ± 2.49
(c)
20.25 ± 6.22
(ab)
17.55 ± 4.57
(bc)
17.65 ± 5.46
(bc)
ALP 13.90 ± 1.41
(b)
20.38 ± 4.37
(a)
15.68 ± 5.82
(b)
14.16 ± 3.67
(b)
14.64 ± 2.30
(b)
15.68 ± 2.37
(b)
Total bilirubin 0.42 ± 0.10
(a)
1.08 ± 1.43
(b)
0.43 ± 0.09
(a)
0.45 ± 0.11
(a)
0.46 ± 0.11
(a)
0.44 ± 0.07
(a)
  1. Data are means ± SD of eight rats in each group.
  2. Data are expressed as Unit/L in GGT, ALP and mg/dL in total bilirubin.
  3. Unshared letters between groups are the significance values at p < 0.001.
  4. Statistical analysis is carried out using one way analysis of variance (ANOVA), CoStat Computer Program.