Microbial caecal content. (A) bifidobacterium spp., (B) lactobacillus spp., (C) bacteroides-prevotella. Bacterial quantities are expressed as Log10 (bacterial cells/g caecal content). Data are the mean ± SEM. *: mean values significantly different (P < 0.05, Student's t-test). -3/+: mice fed with a control diet (n = 9), n-3/+ FOS: mice fed a control diet and supplemented with a prebiotic for 24 days (n = 10), n-3/-: mice fed an n-3 PUFA-depleted diet (n = 12), n-3/- FOS: mice fed an n-3 PUFA-depleted diet and supplemented with a prebiotic for 24 days (n = 12).