Figure 6

Inhibitory effect of CZ on blood glucose after maltose loading in diabetic rats. The diabetic rats fasted for 16 h received maltose (2 g/kg body wt; p.o.) and different doses of CZ (300 mg/kg body wt; p.o. and 600 mg/kg body wt; p.o.) by gastric intubations. Control animals were given only maltose (2 g/kg body wt; p.o.) and the drug control group received maltose (2 g/kg body wt; p.o.) plus acarbose (5 mg/kg). Blood glucose was monitored at 0, 30, 60 and 120 min after food administration. The result shows the significantly impeded 30 minutes post-load glucose level in the CZ 300 mg and CZ 600 mg treated group compared to control. Data are expressed as the mean ± S.E, n = 6. *, P < 0.05 vs. control; **, P < 0.01 vs. control; ***, P < 0.001 vs. control.