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Table 2 Effect of diet on body composition, daily food and energy intake of different mice lines

From: Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes

  DU6 DUhTP
  Standard chow n-3 HFD n-6 HFD Standard chow n-3 HFD n-6 HFD
  LSM ± SE LSM ± SE LSM ± SE LSM ± SE LSM ± SE LSM ± SE
Body weight (bwt) at 87th day (g) 84·0 ± 1·6a, A 96·2 ± 1·7b, A 98·4 ± 1·5b, A 28·.8 ± 1·6a, B 35·4 ± 1·5b, B 32·8 ± 1·6B
Daily food intake (g/d) 11·4 ± 0·2a, A 8·8 ± 0·2b, A 8·8 ± 0·2b, A 5·2 ± 0·2a, B 4·8 ± 0·2a, b, B 4·1 ± 0·2b, B
Daily food intake (g/bwt0.75) 0·41 ± 0·02a 0·29 ± 0·02b 0·28 ± 0·02b 0·42 ± 0·02a 0·33 ± 0·02b 0·30 ± 0·02b
Daily calorie intake (calorie/bwt0.75) 1·24 ± 0·12 1·28 ± 0·12 1·24 ± 0·08 1·25 ± 0·28a 1·49 ± 0·13b 1·32 ± 0·05a, b
Liver (g) 3·7 ± 0·1a, A 4·1 ± 0·1b, A 3·5 ± 0·1a, A 1·1 ± 0·1a, B 1·5 ± 0·1b, B 1·2 ± 0·1a, B
Abdominal fat (g) 2·6 ± 0·3a, A 4·6 ± 0·3b, A 5·2 ± 0·2b, A 0·3 ± 0.3B 1·0 ± 0.2B 0·7 ± 0·3B
Perirenal fat (g) 2·0 ± 0·2a, A 3·4 ± 0·2b, A 3·8 ± 0·2b, A 0·2 ± 0·2B 0·5 ± 0·2B 0·4 ± 0·2B
Brown fat (g) 0·20 ± 0·016a, A 0·26 ± 0·017b, A 0·25 ± 0·015b, A 0·07 ± 0·016B 0·13 ± 0·015B 0·098 ± 0·016B
Liver fat (%) 7.1 ± 0·9a 8·0 ± 1·0a, b 10·2 ± 0·9b, A 6·7 ± 0·9 6·8 ± 0·9 8·7 ± 0·9B
Muscle fat (%) 2·6 ± 0.2 3·5 ± 0·2 2·9 ± ·02 2·9 ± 0·2 3·1 ± 0·1 3·0 ± 0·2
  1. DU6-mouse line selected for high body weight; DUhTP-mouse line selected for high treadmill performance
  2. n-3 and n-6 HFD-high fat diet enriched with either n-3 or n-6 polyunsaturated fatty acids
  3. LSM-Least square means of 8-10 mice per group, SE-Standard error, bwt-body weight, bwt0.75- metabolic body weight
  4. a, b-significant effect of diet at p ≤ 0.05 within the selected line
  5. A, B -significant effect of selection line at p ≤ 0.05 within the feeding group.