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Table 3 Effect of diet on blood parameter of different mice lines

From: Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes

 

DU6

DUhTP

 

Standard chow

n-3 HFD

n-6 HFD

Standard chow

n-3 HFD

n-6 HFD

 

LSM ± SE

LSM ± SE

LSM ± SE

LSM ± SE

LSM ± SE

LSM ± SE

Leptin (ng/ml)

9·8 ± 3·1a, A

27·9 ± 2·6b, A

27·2 ± 5·5b, A

0·8 ± 0·3a, B

2·5 ± 0·6b, B

1·1 ± 0·4a, b, B

Cholesterol (mM)

4·7 ± 0·8

3·5 ± 0·9

5·2 ± 0·8

6·4 ± 0·9a

4·0 ± 0·8b

6·5 ± 0·8a

FFA (mM)

1·2 ± 0·1A

1·2 ± 0·1A

1·4 ± 0·1A

0·8 ± 0·1B

0·5 ± 0·1B

0·8 ± 0·1B

Insulin (ng/ml)

1·38 ± 0·3a, b, A

0·98 ± 0·3a

1·81 ± 0·3b, A

0·23 ± 0·3B

0·21 ± 0·3

0·19 ± 0·3B

Glucose (mM)

8·9 ± 0·8a

11·0 ± 0·8b, A

11·2 ± 0·8b, A

8·9 ± 0·8

8·9 ± 0·8B

7·9 ± 0·8B

  1. DU6-mouse line selected for high body weight; DUhTP-mouse line selected for high treadmill performance
  2. n-3 and n-6 HFD-high fat diet enriched with either n-3 or n-6 polyunsaturated fatty acids
  3. LSM-Least square means of 7-10 mice per group, SE-Standard error; FFA-free fatty acids;
  4. a, b-significant effect of diet at p ≤ 0.05 within the selected line
  5. A, B-significant effect of selection line at p ≤ 0.05 within the feeding group.
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Nutrition & Metabolism

ISSN: 1743-7075

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