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Table 2 Effect of exercise alone or together with Acipimox administration on plasma hormones and biochemical parameters.

From: A higher response of plasma neuropeptide Y, growth hormone, leptin levels and extracellular glycerol levels in subcutaneous abdominal adipose tissue to Acipimox during exercise in patients with bulimia nervosa: single-blind, randomized, microdialysis study

  0 min 45 min 45 min 90 min 90 min
  Basal Exercise Exercise Post-exercise Post-exercise
   + placebo + Aci + placebo + Aci
NPY (pmol/l)      
C group (n = 8) 45 ± 2.3 69.7 ± 19.2** 69 ± 9.2** 45.6 ± 6.7 51.5 ± 12
BN group (n = 8) 53 ± 3.0$ 78.3 ± 15.7**$ 111.4 ± 20.6***$+ 51.2 ± 8.6 65 ± 10.6$
GH (mIU/l)      
C group (n = 8) 7.1 ± 0,5 11.3 ± 2.2*** 40.9 ± 8.7**** 0.7 ± 0.2**** 21.4 ± 8.1****
BN group (n = 8) 11.2 ± 0.9$ 13.1 ± 4.3*** 73.7 ± 23.1****$ 2.01 ± 0.5****$ 28.9 ± 7.5****$
Leptin (ng/ml)      
C group (n = 8) 7.83 ± 1.3 6.52 ± 0.68* 7.73 ± 1.13+ 6.21 ± 0.75* 7.84 ± 0.94#
BN group (n = 8) 6.96 ± 1.1$ 6.31 ± 0.83* 6.8 ± 1.38$+ 5.93 ± 0.69* 7.98 ± 0.99*#
Insulin (mIU/l)      
C group (n = 8) 4.32 ± 0.98 4.05 ± 0.37 2.66 ± 0.98*+ 2.33 ± 0.34* 1.9 ± 0.8**
BN group (n = 8) 2.5 ± 0.59$ 2.32 ± 0.71$ 2.0 ± 0.33* 2.01 ± 0.5* 1.03 ± 0.44**$#
Glucose (mmol/l)      
C group (n = 8) 4.72 ± 0.11 4.8 ± 0.26 4.63 ± 0.19 4.59 ± 0.15 4.33 ± 0.23
BN group (n = 8) 4.33 ± 0.13 4.46 ± 0.38 5.03 ± 0.34*+ 4.07 ± 0.3 4.43 ± 0.26
FFA (mmol/l)      
C group (n = 8) 0.86 ± 0.3 1.54 ± 0.13**** 0.82 ± 0.05+ 0.79 ± 0.05 0.25 ± 0.02****#
BN group (n = 8) 0.79 ± 0.3 1.6 ± 0.28**** 0.79 ± 0.14+ 0.83 ± 0.1 0.26 ± 0.02****#
Glycerol (μmol/l)      
C group (n = 8) 117 ± 33 318 ± 34**** 157.8 ± 18.4++ 85 ± 7.3 44 ± 4.7**#
BN group (n = 8) 82.2 ± 26$ 256 ± 56****$ 114 ± 13$+++ 74 ± 4.2 57 ± 6.2**$#
  1. Values are means ± S.E.M. C = controls (n = 8), BN = bulimia nervosa (n = 8), n = the numbers of subjects are in brackets.
  2. * = P < 0.05, ** = P < 0.01, *** = P < 0.001, **** = P < 0.0001 vs. resting (baseline) values
  3. $ = P < 0.05 BN vs. control subjects (C)
  4. + = P < 0.05 exercise together with Aci administration vs. exercise alone, 45 minutes
  5. + + = P < 0.01 exercise together with Aci administration vs. exercise alone, 45 minutes
  6. +++ = P < 0.001 exercise together with Aci administration vs. exercise alone, 45 minutes
  7. # = P < 0.05 post-exercise recovering phase together with Aci administration vs. post-exercise recovering phase alone, 90 minutes
  8. Effect of 45-min exercise (2 W/kg of lean body mass [LBM]) alone or together with Acipimox (Aci) administration on plasma adipose tissue (AT)-gut-brain peptides, blood glucose, free fatty acids (FFA) and glycerol levels in the controls (C) (n = 8) and bulimia nervosa (BN) patients (n = 8).