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Table 2 Association between compliance at 30 weeks and baseline conditionsa

From: Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program

Variable 30-week Weight available P value 30-week Cholesterol available P value
  Yes (N = 243) No N = (186)   Yes (N = 295) No (N = 128)  
Baseline conditions:
Diabetes N (%) 176 (72) 133 (72) 0.97 220 (75) 88 (69) 0.26
Obesity (BMI> 30) N (%) N (%) 185 (76) 160 (95) 0.011b 232 (79) 108 (84) 0.17
Hyperlipidemia N (%) 151 (62) 104 (56) 0.19 185 (63) 68 (53) 0.065
Hypertension N (%) 155 (64) 115 (62) 0.68 193 (65) 73 (57) 0.10
Metabolic syndrome N (%) 135 (56) 112 (61) 0.33 175 (60) 71 (56) 0.47
Biometrics at week 6:
Weight (kg) 95 ± 22 105 ± 26 < 0.001b 96 ± 22 105 ± 26 0.002b
Waist (cm) 107 ± 15 112 ± 17 0.002b 108 ± 15 112 ± 18 0.046b
Body mass index (kg/m2) 34 ± 7 37 ± 8 < 0.001b 34 ± 7 37 ± 8 0.004b
Systolic blood pressure (mmHg) 126 ± 13 127 ± 15 0.66 126 ± 13 127 ± 15 0.69
Diastolic blood pressure (mmHg) 79 ± 8 79 ± 9 0.78 79 ± 8 79 ± 9 0.90
Heart rate (bpm) 71 ± 11 73 ± 12 0.056 71 ± 11 74 ± 12 0.014b
Metabolic variables at week 6:
Glucose (mg/dL) 101 ± 25 104 ± 27 0.32 101 ± 24 104 ± 30 0.40
   (mmol/L) 5.6 ± 1.4 5.8 ± 1.5   5.6 ± 1.3 5.8 ± 1.7  
Triglycerides (mg/dL) 102 ± 49 115 ± 54 0.02b 103 ± 49 118 ± 57 0.023b
   (mmol/L) 1.2 ± 0.6 1.3 ± 0.6   1.2 ± 0.6 1.3 ± 0.6  
Cholesterol (mg/dL) 164 ± 35 170 ± 38 0.11 164 ± 36 171 ± 37 0.08
   (mmol/L) 4.2 ± 0.9 4.4 ± 1.0   4.2 ± 0.9 4.4 ± 1.0  
High-density lipoprotein (mg/dL) 51 ± 15 48 ± 13 0.08 50 ± 14 49 ± 15 0.33
   Cholesterol (mmol/L) 1.3 ± 0.4 1.2 ± 0.3   1.3 ± 0.4 1.3 ± 0.4  
Low-density lipoprotein (mg/dL) 92 ± 29 99 ± 34 0.06 93 ± 30 99 ± 33 0.11
   Cholesterol (mmol/L) 2.4 ± 0.7 2.6 ± 0.9   2.4 ± 0.8 2.6 ± 0.9  
Change in biometrics from baseline to six weeks:
Weight (kg) -4.0 ± 2.5 -3.6 ± 2.8 0.16 -4.1 ± 2.6 -3.1 ± 2.7 < 0.001b
Waist (cm) -4.0 ± 4.1 -4.4 ± 4.2 0.36 -4.2 ± 4.1 -4.0 ± 4.4 0.66
Body mass index (kg/m2) -1.4 ± 0.9 -1.3 ± 1.0 0.12 -1.5 ± 0.9 -1.1 ± 0.9 < 0.001b
Systolic blood pressure (mmHg) -5.1 ± 15.7 -5.1 ± 15.2 0.98 -5.8 ± 15.1 -3.7 ± 16.6 0.24
Diastolic blood pressure (mmHg) -2.7 ± 8.6 -3.9 ± 10.9 0.24 -3.1 ± 9.2 -3.5 ± 10.7 0.75
Heart rate (bpm) -4.7 ± 1.7 -6.2 ± 11.2 0.20 -5.4 ± 10.9 -5.3 ± 12.8 0.92
Change in metabolic variables from baseline to six weeks:
Glucose (mg/dL) -6 ± 24 -6 ± 25 0.96 -6 ± 22 -7 ± 29 0.67
   (mmol/L) -0.3 ± 1.3 -0.3 ± 1.4   -0.3 ± 1.2 -0.4 ± 1.6  
Triglycerides (mg/dL) -31 ± 55 -23 ± 51 0.12 -32 ± 55 -17 ± 49 0.010b
   (mmol/L) -0.4 ± 0.6 -0.3 ± 0.6   -0.4 ± 0.6 -0.2 ± 0.6  
Cholesterol (mg/dL) -25 ± 26 -17 ± 25 < 0.001b -24 ± 28 -14 ± 19 < 0.001b
   (mmol/L) -0.7 ± 0.7 -0.4 ± 0.6   -0.6 ± 0.7 -0.4 ± 0.5  
High-density lipoprotein (mg/dL) -2.3 ± 7 -1.7 ± 6 0.37 -1.9 ± 7.0 -2.4 ± 6.0 0.50
   Cholesterol (mmol/L) -0.1 ± 0.2 -0.0 ± 0.2   -0.0 ± 0.2 -0.1 ± 0.2  
Low-density lipoprotein (mg/dL) -17 ± 21 -10 ± 21 < 0.001b -17 ± 22 -8 ± 19 < 0.001b
   Cholesterol (mmol/L) -0.5 ± 0.6 -0.3 ± 0.5   -0.4 ± 0.6 -0.2 ± 0.5  
  1. a Statistics represent N (%) and mean ± SD. P values from the chi-square test or t-test, as appropriate.
  2. b Significant if P < 0.05 (no correction testing at multiple weeks, to be conservative).