| |
Control Diet
|
Active Diet
| | |
|---|
| |
Week 0
|
Week 4
|
Change (%)
|
Week 0
|
Week 4
|
Change (%)
|
P
(A-C)
b
|
P
(A-C; weight corrected)
c
|
|
Body weight (kg)d
|
78.9 ± 1.7
|
78.2 ± 1.34h
|
-0.9
|
79.4 ± 1.36i
|
78.0 ± 1.30f
|
-1.8
|
0.0113
| |
|
Cholesterol (mmol/L)
| | |
|
Totald
|
5.73 ± 0.16
|
5.79 ± 1.39
|
1
|
5.81 ± 0.17
|
4.29 ± 0.10f
|
-26
|
< 0.0001
|
< 0.0001
|
|
LDLd
|
3.66 ± 0.15
|
3.70 ± 0.16
|
1
|
3.65 ± 0.16
|
2.42 ± 0.10f
|
-34
|
< 0.0001
|
< 0.0001
|
|
HDLe
|
1.53 ± 0.04
|
1.43 ± 0.04h
|
-7
|
1.54 ± 0.05
|
1.39 ± 0.04g
|
-10
|
0.1637
|
0.1501
|
|
Triglycerides (mmol/L)d
|
1.36 ± 0.11
|
1.38 ± 0.62
|
1
|
1.32 ± 0.09
|
1.07 ± 0.06g
|
-19
|
0.0056
|
0.0011
|
|
Apolipoproteins (g/L)
| | |
|
Apo A-1d
|
1.62 ± 0.03
|
1.54 ± 0.03f
|
5
|
1.62 ± 0.04
|
1.40 ± 0.02f
|
-14
|
< 0.0001
|
< 0.0001
|
|
Apo Bd
|
0.95 ± 0.04
|
0.95 ± 0.03
|
0
|
0.94 ± 0.04
|
0.72 ± 0.02f
|
-23
|
< 0.0001
|
< 0.0001
|
|
Ratios
| | | | | | | | |
|
LDL/HDLd
|
2.53 ± 0.03
|
2.73 ± 0.03h
|
8
|
2.51 ± 0.02
|
1.83 ± 0.03f
|
-27
|
< 0.0001
|
< 0.0001
|
|
ApoB/ApoA-1d
|
0.60 ± 0.03
|
0.63 ± 0.03
|
5
|
0.59 ± 0.03
|
0.53 ± 0.02f
|
-10
|
< 0.0001
|
< 0.0001
|
|
Insulin (mU/L)e
|
6.70 ± 0.42
|
5.70 ± 0.25
|
-14
|
6.08 ± 0.42
|
5.03 ± 0.36h
|
-17
|
0.9410
|
0.9826
|
|
Glucose (mmol/L)d
|
5.21 ± 0.07
|
5.13 ± 0.07
|
-1
|
5.17 ± 0.07
|
5.46 ± 0.08g
|
6
|
0.0002
|
0.0002
|
|
HOMA-IR
|
1.39 ± 0.08
|
1.17 ± 0.08
|
-16
|
1.26 ± 0.09
|
1.09 ± 0.06
|
-14
|
0.7376
|
0.6983
|
|
HbA1c (%)d
|
4.56 ± 0.05
|
4.58 ± 0.05
|
1
|
4.55 ± 0.05
|
4.47 ± 0.05h
|
-2
|
0.0007
|
0.0013
|
|
Free fatty acids (mmol/L)
|
0.37 ± 0.02
|
0.37 ± 0.02
|
0
|
0.37 ± 0.02
|
0.37 ± 0.03
|
0
|
0.9673
|
0.9627
|
|
Blood pressure (mm Hg)
| | |
|
Systolice
|
135 ± 2
|
132 ± 2
|
-2
|
136 ± 2
|
128 ± 2f
|
-8
|
0.0123
|
0.0134
|
|
Diastolic
|
79 ± 1
|
76 ± 1
|
-4
|
79 ± 1
|
76 ± 1
|
-4
|
0.9984
|
0.9265
|
- a Values are means ± SEM. To convert cholesterol and triglyceride values to mg/dL, multiply by 38.67 and 88.57, respectively. To convert apo A-1 and apo B values to mg/dL, multiply by 100.
- bP value for the comparison of changes after Active diet and Control diet.
- cP value for the comparison of changes after Active diet and Control diet, after correction for weight change
- d, e The overall effect of diet was significant: dP < 0.001, eP < 0.05.
- f, g, h Significantly different from baseline (Week 0): fP < 0.0001, gP < 0.001, hP < 0.05.
- iActive diet baseline (Week 0) significantly different from control diet baseline, P < 0.05.
