Table 4 Effect of CD and AD on plasma lipids, parameters of insulin sensitivity and blood pressure^a

Week 0

Week 4

Change (%)

Week 0

Week 4

Change (%)

P (A-C) ^b

P (A-C; weight corrected) ^c

Body weight (kg)^d

78.9 ± 1.7

78.2 ± 1.34^h

-0.9

79.4 ± 1.36ⁱ

78.0 ± 1.30^f

-1.8

0.0113

Cholesterol (mmol/L)

Total^d

5.73 ± 0.16

5.79 ± 1.39

1

5.81 ± 0.17

4.29 ± 0.10^f

-26

< 0.0001

< 0.0001

LDL^d

3.66 ± 0.15

3.70 ± 0.16

1

3.65 ± 0.16

2.42 ± 0.10^f

-34

< 0.0001

< 0.0001

HDL^e

1.53 ± 0.04

1.43 ± 0.04^h

-7

1.54 ± 0.05

1.39 ± 0.04^g

-10

0.1637

0.1501

Triglycerides (mmol/L)^d

1.36 ± 0.11

1.38 ± 0.62

1

1.32 ± 0.09

1.07 ± 0.06^g

-19

0.0056

0.0011

Apolipoproteins (g/L)

Apo A-1^d

1.62 ± 0.03

1.54 ± 0.03^f

5

1.62 ± 0.04

1.40 ± 0.02^f

-14

< 0.0001

< 0.0001

Apo B^d

0.95 ± 0.04

0.95 ± 0.03

0

0.94 ± 0.04

0.72 ± 0.02^f

-23

< 0.0001

< 0.0001

Ratios

LDL/HDL^d

2.53 ± 0.03

2.73 ± 0.03^h

8

2.51 ± 0.02

1.83 ± 0.03^f

-27

< 0.0001

< 0.0001

ApoB/ApoA-1^d

0.60 ± 0.03

0.63 ± 0.03

5

0.59 ± 0.03

0.53 ± 0.02^f

-10

< 0.0001

< 0.0001

Insulin (mU/L)^e

6.70 ± 0.42

5.70 ± 0.25

-14

6.08 ± 0.42

5.03 ± 0.36^h

-17

0.9410

0.9826

Glucose (mmol/L)^d

5.21 ± 0.07

5.13 ± 0.07

-1

5.17 ± 0.07

5.46 ± 0.08^g

6

0.0002

0.0002

HOMA-IR

1.39 ± 0.08

1.17 ± 0.08

-16

1.26 ± 0.09

1.09 ± 0.06

-14

0.7376

0.6983

HbA_1c (%)^d

4.56 ± 0.05

4.58 ± 0.05

1

4.55 ± 0.05

4.47 ± 0.05^h

-2

0.0007

0.0013

Free fatty acids (mmol/L)

0.37 ± 0.02

0.37 ± 0.02

0

0.37 ± 0.02

0.37 ± 0.03

0

0.9673

0.9627

Blood pressure (mm Hg)

Systolic^e

135 ± 2

132 ± 2

-2

136 ± 2

128 ± 2^f

-8

0.0123

0.0134

Diastolic

79 ± 1

76 ± 1

-4

79 ± 1

76 ± 1

-4

0.9984

0.9265