Figure 5
DHA reverses PA-induced inflammation through repressing NLRC4 expression. WT and NLRC4+/− HepG2 cells were treated with different dose of PA with or without DHA preincubation and then cell-free culture supernatants were assayed for IL-1β (A), IL-18 (B), TNF-α (C) and MCP-1 (D) by commercial ELISA kits. The data represent a mean of 4 experiments. *P < 0.05, **P < 0.01 compared with untreated cells; #P < 0.01 versus 0.4 mM PA-treated cells.