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Table 3 AUC GLUCOSE , K ITT and T ½ values during a random-fed insulin tolerance test administered to male and female C57Bl/6 J mice (n = 18 per gender)

From: Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis

 

CONTROL

MSG

ASP

MSG + ASP

p-value

MEAN

SEM

MEAN

SEM

MEAN

SEM

MEAN

SEM

Basal Glucose (mg/dL)

         

male

119.36a

2.80

117.92a

4.71

143.72

5.41b

122.64a

2.90

<.0001

female

112.39ab

4.49

108.50a

1.96

120.33ab**

4.94

125.08b

2.30

<.01

AUCGLUCOSE (mg/dL.min)

        

male

4829.58a

131.96

5522.29ab

152.69

5829.79bc

197.07

6454.79c

266.98

<.0001

female

4819.93

190.36

4717.92**

76.45

5288.33

217.38

5057.92**

233.79

0.156

K. ITT (%/min)

         

male

2.92a

0.28

2.10ab

0.20

2.32a

0.29

1.15b

0.26

0.001

female

2.60

0.37

2.28

0.26

2.40

0.19

1.95*

0.26

0.436

GLUCOSE (min)

         

male

39.69a

14.05

37.91a

3.84

51.61ab

16.63

105.56b

23.72

0.022

female

39.02

6.38

41.54

7.66

32.36

2.90

92.55

36.44

0.105

  1. Significant differences between diets are indicated by different letters abc. *, ** indicate differences between males and females within each diet P < 0.05 and 0.01 respectively.
  2. P-values for comparison of diets are calculated using one way ANOVA, dissimilar means are denoted by different letters abc.
  3. *,** indicate p-value of < .05, <.01 when comparing males to females within each diet group.