Inhibition of TGF-β by a novel PPAR-γ agonist, chrysin, salvages β-receptor stimulated myocardial injury in rats through MAPKs-dependent mechanism

Table 1 Effect of chrysin on histopathological grading

Treatment Groups	Myonecrosis	Inflammatory	Edema
Sham	-	-	-
ISO	+++	+++	+++
Chr15 + ISO	+++	++	++
Chr30 + ISO	++	+	+
Chr60 + ISO	+	+	+
Chr60ps	-	-	-

Score (−): Absence of any myonecrosis, edema and inflammation; Score (+): Focal areas of myonecrosis, edema and inflammation; Score (++): Patchy areas of myonecrosis, edema and inflammation; Score (+++): Confluent areas of myonecrosis, edema and inflammation; Score (++++): Massive areas of myonecrosis, edema and inflammation (n = 6/group).

ISSN: 1743-7075