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Table 3 Islet morphometry

From: Red peppers with moderate and severe pungency prevent the memory deficit and hepatic insulin resistance in diabetic rats with Alzheimer’s disease

  AD-CON (n = 5) AD-LSP (n = 5) AD-MSP (n = 5) AD-SSP (n = 5) Non-AD-CON (n = 5)
β-cell area (%) 5.3 ± 1.1b 6.4 ± 0.9b 5.9 ± 0.8ab 5.7 ± 1.0ab 7.9 ± 1.0a
Individual β-cell size (μm2) 261 ± 30a 228 ± 29b 235 ± 28b 241 ± 27ab 234 ± 27b
Absolute β-cell mass (mg) 21.0 ± 3.1b 24.7 ± 2.9a 24.0 ± 2.9a 23.5 ± 2.8ab 24.9 ± 2.9a
BrdU+ cells (% BrdU+ cells of islets) 0.94 ± 0.13 1.03 ± 0.12 1.05 ± 0.11 1.06 ± 0.12 1.01 ± 0.14
Apoptosis (% apoptotic bodies of islets) 1.19 ± 0.16a 0.97 ± 0.12b 1.02 ± 0.12b 1.02 ± 0.13b 0.95 ± 0.13b
  1. Values are Means ± SD. The β-amyloid (25–35) infused diabetic rats fed high fat diets with 1% dextrin (AD-CON), 1% less pungent red pepper (AD-LSP), moderately pungent red pepper (AD-MSP) or severely pungent red pepper (AD-SSP) for 28 days. The β-amyloid (35–25) infused rats fed high fat diets with 1% dextrin (Non-AD-CON).
  2. abDifferent superscript alphabets on the same row indicate significant differences at P < 0.05.