| |
AD-CON (n = 5)
|
AD-LSP (n = 5)
|
AD-MSP (n = 5)
|
AD-SSP (n = 5)
|
Non-AD-CON (n = 5)
|
|---|
|
β-cell area (%)
|
5.3 ± 1.1b
|
6.4 ± 0.9b
|
5.9 ± 0.8ab
|
5.7 ± 1.0ab
|
7.9 ± 1.0a
|
|
Individual β-cell size (μm2)
|
261 ± 30a
|
228 ± 29b
|
235 ± 28b
|
241 ± 27ab
|
234 ± 27b
|
|
Absolute β-cell mass (mg)
|
21.0 ± 3.1b
|
24.7 ± 2.9a
|
24.0 ± 2.9a
|
23.5 ± 2.8ab
|
24.9 ± 2.9a
|
|
BrdU+ cells (% BrdU+ cells of islets)
|
0.94 ± 0.13
|
1.03 ± 0.12
|
1.05 ± 0.11
|
1.06 ± 0.12
|
1.01 ± 0.14
|
|
Apoptosis (% apoptotic bodies of islets)
|
1.19 ± 0.16a
|
0.97 ± 0.12b
|
1.02 ± 0.12b
|
1.02 ± 0.13b
|
0.95 ± 0.13b
|
- Values are Means ± SD. The β-amyloid (25–35) infused diabetic rats fed high fat diets with 1% dextrin (AD-CON), 1% less pungent red pepper (AD-LSP), moderately pungent red pepper (AD-MSP) or severely pungent red pepper (AD-SSP) for 28 days. The β-amyloid (35–25) infused rats fed high fat diets with 1% dextrin (Non-AD-CON).
-
abDifferent superscript alphabets on the same row indicate significant differences at P < 0.05.
