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Table 2 Effects of ALA on fat depots of WT, AMPKα1 −/− and AMPKα2 −/− mice fed HFD

From: AMP-activated protein kinase is required for the anti-adipogenic effects of alpha-linolenic acid

  WT AMPKα1 −/− AMPKα2 −/−
HF HF-A HF HF-A HF HF-A
Final BW (g) 42.6 ± 3.1 32.6 ± 1.8ab 43.1 ± 3.0 42 ± 3.2 45.5 ± 3.4 44.2 ± 3.7
Epididymal
weight (mg) 2270 ± 158 1224 ± 98ab 2242 ± 201 2137 ± 198 2349 ± 178 2146 ± 184
DNA (μg/mg) 0.32 ± 0.04 0.67 ± 0.05ab 0.29 ± 0.05 0.35 ± 0.06 0.29 ± 0.05 0.36 ± 0.07
Inguinal
Weight (mg) 1090 ± 42 1037 ± 57 1097 ± 45 1058 ± 55 1102 ± 49 1072 ± 59
DNA (μg/mg) 0.42 ± 0.05 0.5 ± 0.06 0.36 ± 0.04 0.39 ± 0.06 0.38 ± 0.05 0.41 ± 0.07
  1. Note: The values are means ± SE. aP < 0.05 for difference between different genotypes with HF-A diet; bP < 0.05 for difference between WT mice. BW, body weight. HF, mice fed high-fat diet; HF-A, mice fed high-fat diet with ALA.