Table 2 Linking the Glucose Ketone Index (GKI) to the therapeutic action of calorie restriction against distal invasion, proliferation, and angiogenesis in the VM-M3 model of glioblastoma
Treatment | Glucose (mM) | Ketone (mM) | GKI | Distal invasion (photons/sec) | Proliferation (Ki67 %) | Angiogenesis (vessels/hpf) |
|---|---|---|---|---|---|---|
AL | 11.2 ± 0.6 | 0.7 ± 0.09 | 15.3 ± 0.9 | 14 ± 1.8 | 48 ± 1.2 | 15 ± 1.1 |
CR | 8.3 ± 0.8 | 1.32 ± 0.1 | 6.5 ± 0.9 | 6 ± 0.9 | 34 ± 1.5 | 7 ± 0.72 |