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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial

Fig. 6

Cell-free DGAT1 inhibition from chromatographic fractionation of GE with overlay of the corresponding LC-MS and LC-UV chromatograms. a The LC-MS chromatogram was generated using base peak index utility to differentiate major compounds. b The LC-UV chromatogram represents the sum of all wavelengths to better show the complex mixture and abundance of phytochemicals in the GE extract. DGAT1 enzyme inhibition (right side x-axis) correlates with the LC-UV pattern and abundance (left side x-axis), showing that multiple phytochemicals in the GE extract are responsible for the observed inhibition. Identities of numbered peaks are given in Table 5

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Nutrition & Metabolism

ISSN: 1743-7075

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