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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: Diet rich in Docosahexaenoic Acid/Eicosapentaenoic Acid robustly ameliorates hepatic steatosis and insulin resistance in seipin deficient lipodystrophy mice

Fig. 3

The improvement of hepatic lipid accumulation of SKO mice after D/E diet. a Histological analysis by hematoxylin/eosin staining for liver sections; (b) Representative photographs of the frozen hepatic sections by Oil Red O staining; (c) Triglyceride (TG) content in liver; (d) Hepatic Cholesterol (TC), free cholesterol (FC) and cholesteryl ester (CE) (n = 15-16); (e) Liver weight (n = 15-16); (f) Body weight (n = 15-16); (g) Liver weight/body weight (n = 15-16). WT, wild type mice; SKO, seipin knockout mice; NC, normal chow diet;D/E, DHA/EPA 3:1 diet. Data are presented as mean ± SEM. ***P < 0.001, SKO NC group compared with WT NC group; #P < 0.05, ##P < 0.01, ###P < 0.001, SKO D/E group compared with SKO NC group

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Nutrition & Metabolism

ISSN: 1743-7075

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