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Table 3 Biochemical and metabolic measures of the 23 women who completed all arms of the study by insulin sensitivity sub-group (IR/IS) after 4 weeks of exposure to the indicated dose of RS. Mean (SD)

From: Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial

 

IR (n = 14)

IS (n = 9)

RS dose (g/day)

RS dose (g/day)

0

15

30

0

15

30

Glucose (mg/dL)*

100.0 (12.3)

98.3 (9.4)

98.2 (13.0)

87.9 (4.5)

86.9 (6.6)

91.6 (8.5)

Insulin (μIU/ml)**

10.3 (4.6)

9.8 (4.6)

9.6 (6.9)

4.0 (1.8)

4.7 (2.0)

4.6 (1.4)

SI [(×10-4 min-1 (μIU/ml)]***

3.80 (1.54)

3.61 (1.60)

4.68 (1.71)

10.59 (5.77)

8.73 (3.61)

8.56 (2.95)

AIRg (μIU/mlx10 min)

510.6 (378.9)

438.1 (342.8)

582.1 (524.4)

380.0 (339.4)

344.1 (257.3)

403.3 (308.6)

DI

2000.2 (2221.0)

1444.7 (1197.6)

2680.8 (2913.2)

3342.9 (2507.4)

2746.7 (2132.2)

3470.9 (2992.3)

SG (min-1)

0.020 (0.015)

0.015 (0.008)

0.021 (0.013)

0.022 (0.007)

0.027 (0.014)

0.023 (0.011)

Total Chol. (mg/dL)

187.6 (38.3)

181.2 (24.4)

190.4 (37.4)

179.6 (32.2)

182.4 (34.1)

190.8 (41.9)

HDL-C (mg/dL)

59.0 (18.0)

58.8 (9.6)

56.9 (14.3)

61.9 (8.1)

62.7 (8.9)

62.9 (12.9)

TG (mg/dL)

111.7 (47.9)

111.8 (50.8)

118.2 (59.1)

83.7 (19.6)

79.1 (27.0)

96.1 (31.1)

Adiponectin (μg/mL)

11.4 (5.7)

11.4 (4.9)

11.5 (5.4)

16.2 (4.6)

16.1 (4.3)

17.7 (6.8)

  1. *P < 0.05, **P < 0.001 for IR vs IS at dose = 0 g/day
  2. ***P < 0.05 for dose effect within the IR sub-group. The 30 g/day dose differed from the 15 g/day dose (P < 0.05) and tended to differ from the 0 g/day dose (P = 0.068)
  3. IR insulin resistant [SI value <7.8 ×10-4 min-1 / (μIU/ml)]
  4. IS insulin sensitive [SI value ≥7.8 ×10-4 min-1 / (μIU/ml)]
  5. S I insulin sensitivity by minimal model
  6. AIRg acute insulin response to glucose
  7. DI disposition index (dimensionless)
  8. S G glucose effectiveness
  9. TG triglycerides