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Table 3 Biochemical and metabolic measures of the 23 women who completed all arms of the study by insulin sensitivity sub-group (IR/IS) after 4 weeks of exposure to the indicated dose of RS. Mean (SD)

From: Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial

  IR (n = 14) IS (n = 9)
RS dose (g/day) RS dose (g/day)
0 15 30 0 15 30
Glucose (mg/dL)* 100.0 (12.3) 98.3 (9.4) 98.2 (13.0) 87.9 (4.5) 86.9 (6.6) 91.6 (8.5)
Insulin (μIU/ml)** 10.3 (4.6) 9.8 (4.6) 9.6 (6.9) 4.0 (1.8) 4.7 (2.0) 4.6 (1.4)
SI [(×10-4 min-1 (μIU/ml)]*** 3.80 (1.54) 3.61 (1.60) 4.68 (1.71) 10.59 (5.77) 8.73 (3.61) 8.56 (2.95)
AIRg (μIU/mlx10 min) 510.6 (378.9) 438.1 (342.8) 582.1 (524.4) 380.0 (339.4) 344.1 (257.3) 403.3 (308.6)
DI 2000.2 (2221.0) 1444.7 (1197.6) 2680.8 (2913.2) 3342.9 (2507.4) 2746.7 (2132.2) 3470.9 (2992.3)
SG (min-1) 0.020 (0.015) 0.015 (0.008) 0.021 (0.013) 0.022 (0.007) 0.027 (0.014) 0.023 (0.011)
Total Chol. (mg/dL) 187.6 (38.3) 181.2 (24.4) 190.4 (37.4) 179.6 (32.2) 182.4 (34.1) 190.8 (41.9)
HDL-C (mg/dL) 59.0 (18.0) 58.8 (9.6) 56.9 (14.3) 61.9 (8.1) 62.7 (8.9) 62.9 (12.9)
TG (mg/dL) 111.7 (47.9) 111.8 (50.8) 118.2 (59.1) 83.7 (19.6) 79.1 (27.0) 96.1 (31.1)
Adiponectin (μg/mL) 11.4 (5.7) 11.4 (4.9) 11.5 (5.4) 16.2 (4.6) 16.1 (4.3) 17.7 (6.8)
  1. *P < 0.05, **P < 0.001 for IR vs IS at dose = 0 g/day
  2. ***P < 0.05 for dose effect within the IR sub-group. The 30 g/day dose differed from the 15 g/day dose (P < 0.05) and tended to differ from the 0 g/day dose (P = 0.068)
  3. IR insulin resistant [SI value <7.8 ×10-4 min-1 / (μIU/ml)]
  4. IS insulin sensitive [SI value ≥7.8 ×10-4 min-1 / (μIU/ml)]
  5. S I insulin sensitivity by minimal model
  6. AIRg acute insulin response to glucose
  7. DI disposition index (dimensionless)
  8. S G glucose effectiveness
  9. TG triglycerides