|
IR (n = 14)
|
IS (n = 9)
|
---|
RS dose (g/day)
|
RS dose (g/day)
|
---|
0
|
15
|
30
|
0
|
15
|
30
|
---|
Glucose (mg/dL)*
|
100.0 (12.3)
|
98.3 (9.4)
|
98.2 (13.0)
|
87.9 (4.5)
|
86.9 (6.6)
|
91.6 (8.5)
|
Insulin (μIU/ml)**
|
10.3 (4.6)
|
9.8 (4.6)
|
9.6 (6.9)
|
4.0 (1.8)
|
4.7 (2.0)
|
4.6 (1.4)
|
SI [(×10-4 min-1 (μIU/ml)]***
|
3.80 (1.54)
|
3.61 (1.60)
|
4.68 (1.71)
|
10.59 (5.77)
|
8.73 (3.61)
|
8.56 (2.95)
|
AIRg (μIU/mlx10 min)
|
510.6 (378.9)
|
438.1 (342.8)
|
582.1 (524.4)
|
380.0 (339.4)
|
344.1 (257.3)
|
403.3 (308.6)
|
DI
|
2000.2 (2221.0)
|
1444.7 (1197.6)
|
2680.8 (2913.2)
|
3342.9 (2507.4)
|
2746.7 (2132.2)
|
3470.9 (2992.3)
|
SG (min-1)
|
0.020 (0.015)
|
0.015 (0.008)
|
0.021 (0.013)
|
0.022 (0.007)
|
0.027 (0.014)
|
0.023 (0.011)
|
Total Chol. (mg/dL)
|
187.6 (38.3)
|
181.2 (24.4)
|
190.4 (37.4)
|
179.6 (32.2)
|
182.4 (34.1)
|
190.8 (41.9)
|
HDL-C (mg/dL)
|
59.0 (18.0)
|
58.8 (9.6)
|
56.9 (14.3)
|
61.9 (8.1)
|
62.7 (8.9)
|
62.9 (12.9)
|
TG (mg/dL)
|
111.7 (47.9)
|
111.8 (50.8)
|
118.2 (59.1)
|
83.7 (19.6)
|
79.1 (27.0)
|
96.1 (31.1)
|
Adiponectin (μg/mL)
|
11.4 (5.7)
|
11.4 (4.9)
|
11.5 (5.4)
|
16.2 (4.6)
|
16.1 (4.3)
|
17.7 (6.8)
|
- *P < 0.05, **P < 0.001 for IR vs IS at dose = 0 g/day
- ***P < 0.05 for dose effect within the IR sub-group. The 30 g/day dose differed from the 15 g/day dose (P < 0.05) and tended to differ from the 0 g/day dose (P = 0.068)
-
IR insulin resistant [SI value <7.8 ×10-4 min-1 / (μIU/ml)]
-
IS insulin sensitive [SI value ≥7.8 ×10-4 min-1 / (μIU/ml)]
-
S
I
insulin sensitivity by minimal model
-
AIRg acute insulin response to glucose
-
DI disposition index (dimensionless)
-
S
G
glucose effectiveness
-
TG triglycerides