| |
Fed animals
|
Overnight starved animals
|
|---|
|
SLD (n = 10)
|
HVLID (n = 10)
|
HLD (n = 9)
|
SLD + S (n = 10)
|
HVLID + S (n = 10)
|
HLD + S (n = 10)
|
|---|
|
Glucose (mmol/l)
|
9.67 ± 0.21
|
chylosity
|
8.58 ± 0.29 a
|
7.17 ± 0.18 b
|
8.84 ± 0.28 a
|
7.96 ± 0.24
|
|
Urea (mmol/l)
|
7.32 ± 0.21
|
9.60 ± 0.14 a
|
8.86 ± 0.32 a
|
6.31 ± 0.25 b
|
8.23 ± 0.24 a,b
|
9.00 ± 0.36 a
|
|
Creatinine (μmol/l)
|
27.9 ± 1.0
|
29.4 ± 1.1
|
27.6 ± 0.6
|
30.2 ± 1.3
|
30.9 ± 1.7
|
29.9 ± 0.85
|
|
ALT (μkat/l)
|
0.88 ± 0.05
|
0.97 ± 0.06
|
1.22 ± 0.03 a,c
|
0.68 ± 0.04 b
|
0.59 ± 0.05 a
|
0.86 ± 0.06 a,b,c
|
|
AST (μkat/l
|
1.35 ± 0.15
|
1.33 ± 0.05
|
1.16 ± 0.06
|
1.26 ± 0.05
|
1.29 ± 0.06
|
1.15 ± 0.05
|
|
Cholesterol (mmol/l)
|
1.64 ± 0.11
|
1.49 ± 0.08
|
1.54 ± 0.12
|
1.42 ± 0.10
|
1.47 ± 0.06
|
1.30 ± 0.07
|
|
HDL cholesterol (mmol/l)
|
1.08 ± 0.12
|
0.99 ± 0.04
|
1.31 ± 0.10 c
|
1.24 ± 0.09
|
1.02 ± 0.04
|
1.16 ± 0.07
|
|
LDL cholesterol (mmol/l)
|
0.29 ± 0.03
|
chylosity
|
0.17 ± 0.03 a
|
0.20 ± 0.03 b
|
0.28 ± 0.02
|
0.12 ± 0.01 c
|
|
Atherogenicity index
|
0.39 ± 0.03
|
0.51 ± 0.05 a
|
0.19 ± 0.02 a,c
|
0.14 ± 0.02 b
|
0.47 ± 0.03 a
|
0.12 ± 0.02 c
|
|
Triglycerides (mmol/l)
|
1.25 ± 0.07
|
0.72 ± 0.08 a
|
0.95 ± 0.06
|
0.79 ± 0.10 b
|
0.60 ± 0.07
|
0.86 ± 0.11
|
|
Total protein (g/l)
|
63.1 ± 0.7
|
63.0 ± 0.7
|
64.6 ± 1.2
|
58.0 ± 0.6 b
|
61.4 ± 0.8 a
|
60.3 ± 0.7 b
|
|
Albumins (mmol/l)
|
35.3 ± 1.4
|
34.7 ± 1.1
|
35.7 ± 1.8
|
33.1 ± 0.8
|
34.8 ± 1.6
|
33.7 ± 1.2
|
- Means ± SE, p ˂ 0.05
-
SLD standard laboratory diet; SLD + S rats fed SLD starved overnight before sacrifice; HVLID diet with high content of valine, leucine, and isoleucine; HVLID + S rats fed HVLID starved overnight before sacrifice; HLD high leucine diet; HLD + S rats fed HLD starved overnight before sacrifice
-
a compared to the corresponding control (SLD or SLD + S)
-
b compared to the corresponding fed group
-
c HLD (HLD + S) vs. HVLID (HVLID + S). Atherogenicity index was calculated as: (cholesterol-HDL cholesterol)/HDL cholesterol
