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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver

Fig. 5

Enrichment of canonical pathways for diet- and genotype-specific comparisons. Legend: Analysis was conducted using the Ingenuity Pathway Analysis tool, based on the Ingenuity Knowledge Base. a 2-way clustering based on pathway significance levels (Fisher’s exact test). Heat-map is color-coded from white to red according to an ascending scale of negative log10P-value. Pathways with a negative log10P ≥ 3 in at least one comparison are shown. b Sharing of common genes among top-ranking pathways in each comparison. Pathways sharing at least 3 genes for any pathway-pair are shown. The number of genes shared between any two pathways are also indicated. J, BALB/cByJ or Acads−/−; KZ, BALB/cByKZ or Acads+/+

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Nutrition & Metabolism

ISSN: 1743-7075

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