Skip to main content

Table 3 Comparison of the levels of alcohol metabolites, nutrient, micronutrients, and physiological factors in the control or AFT groups

From: Alanine-fortified tomatoes relieve the acute alcohol-induced adverse effects in healthy men: a randomized cross-over study

  

18:00

21:00

00:00

6:00

Temporal change

  

(Before alcohol ingestion)

    

Alcohol metabolites

      

 Acetaldehyde (μg/mL)

Control

0 (0)

0.21 (0.20)

0.21 (0.22)

0.02 (0.04)

-

 

AFT

0 (0)

0.33 (0.15)

0.16 (0.13)

0.02 (0.03)

-

 Acetate (μg/mL)

Control

14.1 (3.8)

76.8 (20.3)

66.9 (15.1)

11.4 (3.5)

-

 

AFT

12.4 (4.0)

97.8 (25.4)**

76.5 (15.2)

13.6 (3.8)

-

Nutrients, micronutrients

      

 Glucose (mg/dL)

Control

90 (4)

94 (14)

88 (8)

87 (8)

No significant

 

AFT

91 (6)

86 (11)

89 (5)

88 (6)

No significant

 Alanine (μmol/L)

Control

194 (57)

-

94 (30)

162 (45)

Significant decrease (p < 0.001)

 

AFT

200 (44)

-

396 (122)**

290 (84)**

Significant increase (p < 0.001)

 Vitamin B1 (ng/mL)

Control

5.9 (0.9)

-

-

6.4 (0.9)

Significant increase (p < 0.01)

 

AFT

5.8 (1.0)

-

-

6.1 (1.0)

Significant increase (p < 0.001)

 Vitamin B6 (ng/mL)

Control

12.0 (5.9)

-

-

14.8 (6.6)

Significant increase (p < 0.001)

 

AFT

13.1 (5.6)

-

-

15.8 (6.1)

Significant increase (p < 0.001)

 Folic acid (ng/mL)

Control

5.7 (1.9)

-

-

6.8 (2.1)

Significant increase (p < 0.01)

 

AFT

5.5 (2.2)

-

-

7.7 (2.5)*

Significant increase (p < 0.001)

 Vitamin C (μg/mL)

Control

7.0 (2.5)

-

-

6.4 (2.0)

Significant decrease (p < 0.05)

 

AFT

7.2 (2.1)

-

-

7.0 (2.2)

No significant

Physiological factors

      

 Urinary pH

Control

6.7 (0.8)

5.7 (0.3)

5.8 (0.5)

5.7 (0.8)

Significant decrease (p < 0.05)

 

AFT

6.7 (0.7)

6.1 (0.4)**

6.5 (0.5)**

5.8 (0.4)

Significant decrease (p < 0.001)

 Vasopressin (pg/mL)

Control

4.3 (1.7)

4.5 (1.7)

5.5 (6.0)

6.3 (6.8)

No significant

 

AFT

4.6 (1.8)

4.7 (2.1)

4.6 (1.6)

4.8 (4.8)

No significant

  1. Results are expressed as the means and standard deviation (mean ± SD, n = 15). Asterisks indicate significant differences compared to the control group; *p < 0.05, **p < 0.01, Student’s t-test. Temporal changes of each item were analyzed with a paired t-test or a repeated ANOVA. -; not determined or analyzed. AFT alanine-fortified tomato