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Table 1 Group comparisons for different variables in different Gensini score groups: Continuous variables are given as means ± SD and evaluated using analysis of variance (ANOVA), followed by least significant difference (LSD) test for multiple comparisons. Dichotomous and categorical variables are given as percentages and and compared using Pearson’s χ 2 test

From: Human serum preβ1-high density lipoprotein levels are independently and negatively associated with coronary artery diseases

Variable Group 1 (Gensini score = 0, n = 56) Group 2 (Gensini score = 0 ~ 60, n = 22) Group 3 (Gensini score >60, n = 24) p value
Male (N%) 43 (76.8 %) 18 (81.8 %) 18 (75.0 %) 0.845
Age (years) 59.75 ± 12.67 57.82 ± 13.83 65.83 ± 9.70 0.062
BMI (kg/m2) 23.85 ± 4.21 25.58 ± 3.18 23.39 ± 3.30 0.122
Smoking (N%) 3 (18.8 %) 15 (68.2 %) 13 (54.2 %) 0.009
0.003 (Group 1 vs. 2)
0.025 (Group 1 vs. 3)
0.331 (Group 2 vs. 3)
Hypertension (N%) 9 (56.2 %) 12 (54.5 %) 14 (58.3 %) 0.967
DM (N%) 2 (12.5 %) 4 (18.2 %) 6 (25.0 %) 0.609
TC (mmol/L) 4.35 ± 0.74 4.20 ± 1.14 4.52 ± 1.10 0.507
TG (mmol/L) 1.29 ± 0.56 1.62 ± 0.93 1.71 ± 1.27 0.077
HDL-C (mmol/L) 1.39 ± 0.31 1.09 ± 0.19 1.14 ± 0.29 <0.0001
<0.0001 (Group 1 vs. 2)
<0.0001 (Group 1 vs. 3)
0.507 (Group 2 vs. 3)
LDL-C (mmol/L) 2.39 ± 0.58 2.38 ± 0.90 2.62 ± 0.84 0.381
ApoAI (mg/mL) 0.97 ± 0.13 0.98 ± 0.15 1.08 ± 0.23 0.078
ApoB (mg/mL) 0.70 ± 0.19 0.82 ± 0.29 0.88 ± 0.30 0.143
ApoE (mg/L) 43.52 ± 12.78 46.05 ± 17.38 51.87 ± 20.65 0.309
Lp (a) (mg/L) 187.40 ± 182.46 191.16 ± 179.62 188.22 ± 191.16 0.998
HDL-(A) (%) 1.94 ± 0.77 1.48 ± 0.64 1.81 ± 0.71 0.048
0.014 (Group 1 vs. 2)
0.451 (Group 1 vs. 3)
0.135 (Group 2 vs. 3)
HDL-(B) (%) 19.11 ± 6.73 13.70 ± 4.77 15.46 ± 6.24 0.001
0.011 (Group 1 vs. 2)
0.018 (Group 1 vs. 3)
0.343 (Group 2 vs. 3)
HDL-(C) (%) 10.45 ± 2.36 11.15 ± 2.97 9.69 ± 2.89 0.171
Preβ1-HDL (%) 1.69 ± 0.34 1.48 ± 0.47 1.24 ± 0.42 <0.0001
0.032 (Group 1 vs. 2)
<0.0001 (Group 1 vs. 3)
0.047 (Group 2 vs. 3)
LDL (%) 41.90 ± 5.88 42.81 ± 7.02 44.34 ± 5.92 0.268
IDL (%) 3.58 ± 1.06 5.14 ± 1.71 6.02 ± 2.28 <0.0001
<0.0001 (Group 1 vs. 2)
<0.0001 (Group 1 vs. 3)
0.006 (Group 2 vs. 3)
VLDL (%) 16.37 ± 6.10 20.12 ± 8.38 17.95 ± 8.24 0.116
  1. BMI body mass index, DM diabetes mellitus, TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, ApoAI apolipoprotein A, ApoB apolipoprotein B, ApoE apolipoprotein E, Lp (a) Lipoprotein (a). The sum of the peak areas (after scanning see Fig. 1) was taken as the total amount of plasma lipoproteins, and the percentage (%) of each lipoprotein fraction was calculated automatically by the densitometer