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Table 2 HCAL diet affects maternal liver fatty acid profiles. No effect of metformin

From: The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism

Fatty acid NORM mean (±SD) HCAL mean (±SD) HCAL + MET mean (±SD)
SFA 14.0 0.6 (±0.14) 1.3 (±0.24)a** 1.2 (±0.20)
16.0 28.5 (±1.90) 32.7 (±2.35)a* 33.4 (±2.25)
18.0 6.7 (±0.44) 6.3 (±1.89) 6.5 (±0.60)
MUFA 16.1n7 2.1 (±0.47) 4.2 (±0.89)a* 3.7 (±0.47)
18.1n9 33.2 (±1.43) 41.4 (±1.04)a* 41.3 (±1.79)
18.1n7 4.1 (±0.29) 4.4 (±0.44) 4.2 (±0.74)
PUFA 18.2n6 19.5 (±2.60) 8.3 (±1.41)a* 8.1 (±1.10)
18.3n3 0.8 (±0.10) 0.3 (±0.19)a* 0.2 (±0.21)
20.4n6 2.6 (±0.74) 1.1 (±0.34)a* 1.1 (±0.39)
22.6n3 1.6 (±0.63) 0.3 (±0.23)a* 0.2 (±0.22)
  1. NORM normal diet, HCAL high calorie diet, MET metformin, SD standard deviation, SFA saturated fatty acids, MUFA monounsaturated fatty acids, PUFA polyunsaturated fatty acids
  2. aNORM vs. HCAL; *p < 0.05, **p < 0.01
  3. Data are expressed as mean ± SD (mg/100 mg)