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Table 1 Effects of fructose- and sucrose-enriched diets on the development of MetS

From: Animal models of metabolic syndrome: a review

Researchers (Year) Types of diet Treatment length Strains of animal Components of metabolic syndrome
Obesity Hyperglycemia Hypertension Dyslipidemia
Thirunavukkarasu et al. [41] High-fructose diet 3 weeks Male Wistar rats - -
Sanchez-Lozada et al. [42] High-fructose diet (60 %) 8 weeks Male Sprague-Dawley rats - -
Fructose drinking water (10 %) - -
Shahraki et al. [105] High-fructose diet 8 weeks Male Wistar rats -
Mahmoud and Elshazly [106] Fructose drinking water (10 %) 12 weeks Male Wistar rats
Mansour et al. [107] High-fructose diet 16 weeks Male Wistar albino rats -
Mamikutty et al. [108] Fructose drinking water 8 weeks Male Wistar rats
Di Luccia et al. [109] High-fructose diet 8 weeks Male Sprague-Dawley rats -
Jurgens et al. [35] Fructose drinking water (15 %) 10 weeks Male NMRI mice - - -
Sucrose soft drink (10 %) - - -
Non-caloric soft drink - - -
Oron-Herman et al. [51] High-sucrose diet 7 weeks Male spontaneously hypertensive rats
High-fructose diet Male Sprague-Dawley rats
Aguilera et al. [45] Sucrose drinking water (30 %) 21 weeks Male Wistar rats -
Vasanji et al. [49] Sucrose drinking water (32 %) 10 weeks Male Sprague-Dawley rats - -
Pang et al. [50] High-sucrose diet 6 weeks Male Sprague-Dawley rats -
  1. Table represents the effects of fructose- and sucrose-enriched diets on each component of MetS. The symbol ‘’ and ‘✗’ indicate the presence and absence of significant effect of the sign of MetS respectively, while ‘-’ indicates the effects on the component not being evaluated in the study