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Table 1 Characteristics of healthy adult volunteers

From: Hormonal responses to non-nutritive sweeteners in water and diet soda

Variable Study arm 1 (mean ± SD) Study arm 2 (mean ± SD) p-valueb
Age (years) 29.7 ± 7.6 27.4 ± 6.7 0.21
Female Gender 53 % 55 % 0.81
Race (%)    0.02
 White 60 % 42 %  
 Black 37 % 32 %  
 Other 3 % 26 %  
Body Mass Index (BMI, kg/m2) 25.8 ± 4.2 26.3 ± 7.5 0.77
Weight Status (%)    0.56
 Normal Weight 53 % 58 %  
 Overweight 23 % 16 %  
 Obese 23 % 26 %  
Glucose (umol/L) 4.6 ± 0.3 4.8 ± 0.35 0.08
Insulin (pmol/L) 32.7 ± 15.6 51.5 ± 42.1 0.03
C-Peptide (nmol/L) 0.4 ± 0.1 0.7 ± 0.3 0.0006
HOMA-2 0.9 ± 0.3 1.5 ± 0.7 0.0001
Hemoglobin A1c (%) 5.3 ± 0.3 5.2 ± 0.4 0.32
Triglycerides (mmol/L) 0.8 ± 0.3 1.1 ± 0.7 0.07
HDL (mmol/L) 1.5 ± 0.3 1.5 ± 0.4 0.87
LDL (mmol/L) 2.4 ± 0.7 2.4 ± 0.8 0.95
Total cholesterol (mmol/L) 4.3 ± 0.8 4.4 ± 0.9 0.61
NNS Beverage Consumption (%)a    0.005
 Never 57 % 40 %  
  ≥ 1/month 26 % 53 %  
  ≥ 1/day 17 % 7 %  
NNS Packet Use (%)a    0.52
 Never 70 % 73 %  
  ≥ 1/month 23 % 17 %  
  ≥ 1/day 7 % 10 %  
  1. aDifferent questionnaires were used to assess NNS consumption in Study Arm 1 and Study Arm 2
  2. bValues in bold reflect statistical significance using a cut-off of p<0.05