Fig. 3

Fold changes from baseline in expression of genes involved in fatty acid uptake and metabolism in MNC after ingesting a (a) high-carbohydrate or a (b) high-fat meal between lean and obese subjects. Significant differential responses, as analysed by linear mixed model, were found after high-carbohydrate meal in expression of: FAT/CD36 (P group = 0.040 and time × group =0.040), FASN (P group = 0.083, and time × group =0.083), and ACC2 (P group = 0.033, and time × group =0.033). Significant differences at a single time point (120 min or 360 min) between the two groups, as tested by independent sample t-test, have been presented in the figure. Data presented as mean ± SEM. Lean —, ●; obese ----, ○; * P < 0.05