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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling

Fig. 6

Cardiac left ventricular end-diastolic pressure in Langendorff perfused ex vivo mice hearts. Left ventricular end-diastolic pressure (LVEDP) were registered at stabilization and during the post-ischemic reperfusion period in hearts exposed to either a normal chow diet (ND) or a high fat diet (HFD) in: a wild type (wt), b Epac1 deficient (Epac1−/−) and c Epac2 deficient (Epac2−/−) mice hearts. Values are mean ± SEM. * p < 0.05 vs. wt ND. # p < 0.05 vs. corresponding pre-ischemic stabilization value

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