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Table 4 Association between single nucleotide polymorphisms (SNPs) at lipoprotein lipase gene and lipid traits

From: High fat diet modifies the association of lipoprotein lipase gene polymorphism with high density lipoprotein cholesterol in an Asian Indian population

SNPs

Total cholesterol mmol/l

Triglycerides mmol/l

LDL-C mmol/l

SNP rs4922115

 GG

4.9 ± 1.1

1.6 ± 1.0

3.1 ± 0.9

 GA

4.8 ± 1.1

1.9 ± 1.8

3.0 ± 0.9

 AA

4.7 ± 0.9

1.7 ± 0.8

2.9 ± 0.8

Dominant model (GG vs GA + AA) (P value)

0.4

0.001

0.1

SNP rs1121923

 CC

4.8 ± 1.1

1.7 ± 1.4

3.0 ± 0.9

 CT

5.1 ± 1.0

1.7 ± 1.0

3.2 ± 0.9

 TT

4.9 ± 0.6

1.4 ± 0.4

3.3 ± 0.4

Dominant model (CC vs CT + TT) (P value)

0.4

0.3

0.9

SNP rs328

 CC

4.9 ± 1.0

1.7 ± 1.1

3.1 ± 0.9

 CG

4.9 ± 1.1

1.5 ± 0.9

3.1 ± 0.9

 GG

5.0 ± 0.9

1.4 ± 0.5

3.2 ± 0.8

Dominant model (CC vs CG + GG) (P value)

0.3

0.1

0.3

SNP rs285

 CC

4.8 ± 1.1

1.7 ± 1.2

3.0 ± 0.8

 CT

4.8 ± 1.1

1.5 ± 0.9

3.1 ± 0.9

 TT

4.8 ± 1.0

1.4 ± 0.8

3.0 ± 0.8

Dominant model (CC vs CT + TT) (P value)

0.7

0.00009

0.4

  1. LDL-c Low density lipoprotein cholesterol
  2. Results are expressed as mean ± SD
  3. P values adjusted for age, gender, body mass index and type 2 diabetes
  4. Those p values that are in bold implicates those values that are significant after Bonferroni correction