Skip to main content

Table 3 Cardiometabolic risk markers before and after 12 weeks supplementation with flaxseed fibers (FF) and/or dairy calcium (Ca) in addition to alli®*

From: Supplementation with dairy calcium and/or flaxseed fibers in conjunction with orlistat augments fecal fat excretion without altering ratings of gastrointestinal comfort

      

P-values**

  

FF-

FF+

 

Intervention

  

Ca- (n = 6)

Ca + (n = 12)

Ca- (n = 10)

Ca + (n = 10)

Baseline

FF

Ca

Body weight (kg)

Baseline

98.9 ± 8.4

103.4 ± 5.2

91.2 ± 3.9

95.6 ± 2.8

0.30

  

Week 12

94.0 ± 9.9

98.9 ± 4.9

87.4 ± 3.8

91.4 ± 2.4

 

0.46

0.80

WC (cm)

Baseline

111.0 ± 4.8

111.3 ± 3.4

104.5 ± 2.6

104.2 ± 3.2

0.56

  

Week 12

104.9 ± 6.3ab

107.5 ± 3.2a

101.8 ± 2.7a

98.4 ± 2.9b

 

FF × Ca: 0.03*

Systolic BP (mmHg)

Baseline

116 ± 6

118 ± 2

113 ± 2

123 ± 4

0.52

  

Week 12

116 ± 5

114 ± 3

115 ± 3

129 ± 5

 

0.58

0.70

Diastolic BP (mmHg)

Baseline

82 ± 3

81 ± 3

78 ± 2

84 ± 2

0.23

  

Week 12

80 ± 4

79 ± 2

75 ± 3

84 ± 2

 

0.03*

0.61

TAG (mmol/L)

Baseline

0.85 ± 0.33

1.46 ± 0.23

1.65 ± 0.25

0.99 ± 0.25

0.15

  

Week 12

0.85 ± 0.18

1.27 ± 0.14

1.17 ± 0.14

0.92 ± 0.14

 

0.42

0.56

T-C (mmol/L)

Baseline

4.87 ± 0.39

5.29 ± 0.28

5.31 ± 0.30

5.62 ± 0.30

0.52

  

Week 12

2.39 ± 0.38

4.94 ± 0.27

4.95 ± 0.30

5.11 ± 0.30

 

0.95

0.87

LDL-C (mmol/L)

Baseline

2.94 ± 0.33

3.24 ± 0.24

3.31 ± 0.26

3.28 ± 0.26

0.82

  

Week 12

2.52 ± 0.30

3.09 ± 0.21

3.12 ± 0.24

2.98 ± 0.24

 

0.98

0.62

HDL-C (mmol/L)

Baseline

1.45 ± 0.10

1.30 ± 0.07

1.18 ± 0.06

1.65 ± 0.09

0.17

  

Week 12

1.35 ± 0.15

1.15 ± 0.05

1.18 ± 0.06

1.52 ± 0.08

 

0.19

0.81

Glucose (mmol/L)

Baseline

5.38 ± 0.19

5.34 ± 0.13

5.24 ± 0.15

5.42 ± 0.15

0.84

  

Week 12

5.29 ± 0.20

5.34 ± 0.14

5.30 ± 0.16

5.19 ± 0.16

 

0.40

0.32

Insulin (pmol/L)

Baseline

83.9 ± 26.6

103.3 ± 18.8

102.4 ± 20.6

73.4 ± 20.6

0.67

  

Week 12

62.0 ± 38.3

114.6 ± 24.7

83.0 ± 27.1

70.0 ± 27.1

 

0.52

0.25

HOMA-IR

Baseline

2.92 ± 0.58

3.54 ± 0.63

3.65 ± 1.21

2.59 ± 0.41

0.68

  

Week 12

2.10 ± 0.46

3.99 ± 1.31

2.96 ± 0.80

2.34 ± 0.47

 

0.97

0.67

HbA1c (%)

Baseline

5.32 ± 0.05a

5.59 ± 0.08b

5.50 ± 0.09ab

5.57 ± 0.12b

0.03*

  

Week 12

5.38 ± 0.10

5.48 ± 0.08

5.48 ± 0.09

5.47 ± 0.10

   

hsCRP (pg/mL)

Baseline

3.23 ± 1.76

3.11 ± 1.15

4.81 ± 1.43

7.61 ± 2.41

0.92

  

Week 12

3.93 ± 0.70

2.07 ± 0.45

5.06 ± 1.61

5.80 ± 1.90

 

0.03*

0.61

  1. Abbreviations: BMI body mass index, BP blood pressure, HDL-C HDL cholesterol, hsCRP high sensitivity C-reactive protein, HOMA-IR Homeostasis Model of Assessment - Insulin Resistance, HbA1c glycated hemoglobin, LDL-C LDL cholesterol, TAG triacylglycerol, T-C total cholesterol, WC waist circumference
  2. * n = 39; completers only population
  3. ** P-values refer to an ANCOVA model with adjustment for baseline value, sex and age. Columns with different superscript letters are significantly different; P<0.05
Back to article page

Nutrition & Metabolism

ISSN: 1743-7075

Contact us