| |
Unit
|
PRE
|
POST
|
Reference range
|
P-value
|
|---|
|
Glucose and lipids
|
|
Glucose
|
mg/dl
|
91.4 ± 7.3
|
88.7 ± 5.3
|
74–106
|
0.009
|
|
TG
|
mg/dl
|
64 (38–212)
|
62 (39–172)
|
<150
|
0.089
|
|
HDL-C
|
mg/dl
|
71.3 ± 14.3
|
73.6 ± 15.6
|
>40
|
0.088
|
|
LDL-C
|
mg/dl
|
110.9 ± 31.3
|
122.8 ± 33.6
|
<160
|
0.001
|
|
TC
|
mg/dl
|
186.5 ± 34.7
|
195.3 ± 34.7
|
<200
|
0.019
|
|
LDL-C/HDL-C
| |
1.47 (0.50–3.62)
|
1.58 (0.56–2.92)
|
<4.5
|
0.084
|
|
TG/HDL-C
| |
0.89 (0.43–4.24)
|
0.76 (0.48–3.37)
|
<2
|
0.039
|
|
Hormones
|
|
TSH
|
μU/ml
|
1.81 (0.01–7.26)
|
1.87 (0.15–10.29)
|
0.27–4.20
|
0.202
|
|
fT3
|
pmol/l
|
4.91 (3.84–10.87)
|
4.11 (2.91–8.80)
|
3.4–6.8
|
<0.001
|
|
fT4
|
pmol/l
|
15.7 (11.9–37.1)
|
16.4 (12.6–36.2)
|
10.6–22.7
|
0.008
|
|
Insulin
|
pmol/l
|
55.3 ± 23.7
|
43.0 ± 19.7
|
18–173
|
0.001
|
|
IGF-1
|
ng/ml
|
175 (52–427)
|
140 (31–337)
|
72–457
|
<0.001
|
|
Liver and kidney parameters
|
|
CRP
|
mg/l
|
0 (0–11)
|
0 (0–21)
|
<5
|
0.327
|
|
Albumin
|
g/dl
|
4.51 ± 0.24
|
4.55 ± 0.24
|
3.5–5.2
|
0.215
|
|
GOT
|
U/l
|
21 (12–43)
|
23 (12–51)
|
10–50
|
0.410
|
|
GPT
|
U/l
|
19 (12–37)
|
22 (12–57)
|
10–50
|
0.012
|
|
Alkaline Phosphatase
|
U/l
|
56.3 ± 17.0
|
52.1 ± 15.3
|
35–130
|
0.001
|
|
Total bilirubin
|
mg/dl
|
0.5 (0.2–2.2)
|
0.4 (0.2–1.4)
|
<0.9–1.4
|
0.088
|
|
Creatinine
|
mg/dl
|
0.89 ± 0.13
|
0.88 ± 0.15
|
0.51–1.17
|
0.185
|
|
Urea
|
mg/dl
|
30.3 ± 8.8
|
34.9 ± 9.3
|
12.8–42.8
|
<0.001
|
|
Uric acid
|
mg/dl
|
4.1 (2.9–7.0)
|
4.5 (2.3–8.1)
|
2.4–7
|
0.001
|
|
Micronutrients
|
|
Potassium
|
mmol/l
|
4.4 (3.6–5.4)
|
4.3 (3.8–5.2)
|
3.5–5.1
|
0.180
|
|
Calcium
|
mg/dl
|
2.34 ± 0.08
|
2.33 ± 0.07
|
2.15–2.50
|
0.411
|
|
Magnesium
|
mmol/l
|
0.82 ± 0.05
|
0.82 ± 0.06
|
0.66–1.07
|
0.721
|
|
Iron
|
μg/dl
|
100.9 ± 50.0
|
77.3 ± 32.2
|
37–158
|
0.002
|
|
Folic acid
|
ng/ml
|
7.81 ± 3.32
|
10.04 ± 3.92
|
4.6–18.7
|
<0.001
|
|
Blood count
|
|
Leucocytes
|
103/μl
|
5.73 (3.44–11.07)
|
5.66 (2.90–11.58)
|
3.9–10.4
|
0.457
|
|
Thrombocytes
|
103/μl
|
255.8 ± 52.8
|
240.6 ± 53.4
|
146–391
|
0.002
|
|
Erythrocytes
|
106/μl
|
4.66 ± 0.32
|
4.72 ± 0.31
|
4.0–5.8
|
0.056
|
|
Haemoglobin
|
g/dl
|
13.9 ± 1.0
|
14.1 ± 0.9
|
11.6–17.6
|
0.068
|
|
Haematocrit
|
%
|
40.3 ± 2.7
|
40.7 ± 2.6
|
34.6–50.6
|
0.163
|
|
MCH
|
pg
|
29.8 ± 1.1
|
29.8 ± 1.1
|
27–34
|
0.415
|
|
MCHC
|
g/dl
|
34.4 (32.5–37.1)
|
34.4 (32.7–36.0)
|
31.5–36.3
|
0.333
|
|
MCV
|
10−9μl
|
86.7 ± 3.4
|
86.3 ± 3.4
|
81–100
|
0.061
|
-
Abbreviations: CRP C-reactive protein, C cholesterol, GOT glutamic-oxaloacetic transaminase, GPT glutamic-pyruvic transaminase, HDL high-density lipoprotein, IGF-1 insulin-like growth factor 1, LDL low-density lipoprotein, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, MCV mean corpuscular volume, fT3 free triiodothyronine, fT4 free thyroxine, TC total cholesterol, TG triglycerides, TSH thyroid stimulating hormone
