| |
Postprandial time point
| | | |
|---|
| |
0 hour
|
1 hour
|
3 hour
|
6 hour
|
Treatment effect p-value
|
Time effect p-value
|
Time x treatment interaction p-value
|
|---|
|
C1CP (ng/ml)
| | | | |
0.093
|
0.084
|
0.195
|
|
PO + MFGM
|
134.4 ± 140.6
|
131.1 ± 134.1
|
128.1 ± 119.9
|
131.3 ± 127.7
| | | |
|
PO
|
122.0 ± 133.7
|
127.1 ± 138.7
|
117.5 ± 124.2
|
127.9 ± 152.0
| | | |
|
WC + MFGM
|
130.0 ± 135.2
|
126.2 ± 137.0
|
130.1 ± 146.5
|
129.3 ± 125.9
| | | |
|
WC
|
153.1 ± 269.9
|
137.8 ± 201.7
|
123.6 ± 133.8
|
129.2 ± 146.3
| | | |
|
CTX (ng/ml)
| | | | |
0.0001
|
<0.0001
|
<.0001
|
|
PO + MFGM
|
0.57 ± 0.27
|
0.33 ± 0.14
|
0.24 ± 0.12
|
0.32 ± 0.16
| | | |
|
PO
|
0.53 ± 0.22
|
0.31 ± 0.13
|
0.24 ± 0.12
|
0.44 ± 0.22
| | | |
|
WC + MFGM
|
0.56 ± 0.27
|
0.33 ± 0.16
|
0.22 ± 0.11
|
0.26 ± 0.14
| | | |
|
WC
|
0.55 ± 0.26
|
0.31 ± 0.11
|
0.20 ± 0.09
|
0.38 ± 0.20
| | | |
|
IL-6 (pg/ml)
| | | | |
0.449
|
<0.0001
|
0.975
|
|
PO + MFGM
|
0.72 ± 1.37
|
0.59 ± 1.26
|
0.54 ± 0.98
|
0.76 ± 1.40
| | | |
|
PO
|
0.74 ± 1.08
|
0.59 ± 0.87
|
0.61 ± 1.09
|
0.76 ± 1.16
| | | |
|
WC + MFGM
|
0.78 ± 1.43
|
0.63 ± 1.27
|
0.60 ± 1.20
|
0.86 ± 1.48
| | | |
|
WC
|
0.70 ± 1.10
|
0.63 ± 1.18
|
0.60 ± 1.13
|
0.87 ± 1.51
| | | |
|
IL-18 (pg/ml)
| | | | |
0.671
|
<0.0001
|
0.245
|
|
PO + MFGM
|
11.11 ± 3.33
|
11.32 ± 3.32
|
10.72 ± 2.74
|
10.80 ± 3.39
| | | |
|
PO
|
11.24 ± 3.10
|
10.51 ± 3.34
|
9.629 ± 3.15
|
10.96 ± 2.95
| | | |
|
WC + MFGM
|
11.79 ± 3.64
|
10.63 ± 4.11
|
10.40 ± 3.67
|
10.81 ± 3.17
| | | |
|
WC
|
11.05 ± 3.44
|
10.98 ± 3.03
|
10.09 ± 2.69
|
10.18 ± 3.06
| | | |
|
TNFα (pg/ml)
| | | | |
0.679
|
<0.0001
|
0.303
|
|
PO + MFGM
|
2.34 ± 0.67
|
2.36 ± 0.66
|
2.27 ± 0.62
|
2.22 ± 0.68
| | | |
|
PO
|
2.49 ± 0.71
|
2.36 ± 0.56
|
2.29 ± 0.63
|
2.36 ± 0.64
| | | |
|
WC + MFGM
|
2.54 ± 0.83
|
2.36 ± 0.81
|
2.32 ± 0.81
|
2.32 ± 0.73
| | | |
|
WC
|
2.44 ± 0.70
|
2.38 ± 0.67
|
2.27 ± 0.57
|
2.32 ± 0.63
| | | |
|
CRP (mg/l)
| | | | |
0.207
|
<0.0001
|
0.608
|
|
PO + MFGM
|
1.49 ± 0.85
|
1.51 ± 0.86
|
1.46 ± 0.85
|
1.52 ± 0.87
| | | |
|
PO
|
1.55 ± 0.86
|
1.65 ± 0.87
|
1.58 ± 0.88
|
1.62 ± 0.87
| | | |
|
WC + MFGM
|
1.49 ± 0.85
|
1.56 ± 0.90
|
1.51 ± 0.87
|
1.56 ± 0.88
| | | |
|
WC
|
1.49 ± 0.83
|
1.58 ± 0.90
|
1.50 ± 0.84
|
1.53 ± 0.86
| | | |
|
IL-10 (pg/ml)
| | | | |
0.278
|
0.206
|
0.012
|
|
PO + MFGM
|
0.49 ± 1.17
|
0.52 ± 1.19
|
0.52 ± 1.12
|
0.57 ± 1.14
| | | |
|
PO
|
0.56 ± 1.37
|
0.54 ± 1.35
|
0.54 ± 1.22
|
0.51 ± 1.32
| | | |
|
WC + MFGM
|
0.52 ± 1.08
|
0.57 ± 1.09
|
0.57 ± 1.04
|
0.58 ± 1.17
| | | |
|
WC
|
0.52 ± 1.13
|
0.58 ± 1.15
|
0.58 ± 1.21
|
0.55 ± 1.28
| | | |
|
sICAM (mg/l)
| | | | |
0.168
|
<0.0001
|
0.114
|
|
PO + MFGM
|
0.96 ± 0.51
|
0.97 ± 0.51
|
0.95 ± 0.51
|
0.97 ± 0.53
| | | |
|
PO
|
0.97 ± 0.51
|
1.058 ± 0.54
|
1.00 ± 0.51
|
1.044 ± 0.54
| | | |
|
WC + MFGM
|
0.93 ± 0.50
|
0.99 ± 0.53
|
0.97 ± 0.54
|
0.97 ± 0.51
| | | |
|
WC
|
0.92 ± 0.48
|
1.00 ± 0.52
|
0.96 ± 0.49
|
0.96 ± 0.49
| | | |
- Actual (untransformed) values are presented here; analysis was done on the transformed data. N = 36
- Test meals: palm oil plus milk fat globule membrane (PO + MFGM), palm oil (PO), whipping cream plus milk fat globule membrane (WC + MFGM), whipping cream (WC)
- Bone variables: type 1 C-terminal collagen propeptide (C1CP), C-telopeptide of type 1 collagen (CTX)
- Inflammatory variables: interleukin-6 (IL-6), interleukin-18 (IL-18), tumor necrosis factor alpha (TNFα), C-reactive protein (CRP), interleukin-10 (IL10), soluble intercellular adhesion molecule (sICAM)
