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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes

Fig. 3

Dose-dependent effects of DHA and EPA on adiponectin synthesis and secretion. 3T3-L1 adipocytes were incubated with different doses (25, 50, 100 and 200 μmol/L) of DHA or EPA for 24 h, while BSA treatment served as the control. Cellular adiponectin (a, b, c) and secreted adiponectin (d) were assessed. Cellular adiponectin in treatment groups were normalized to the control with β-actin worked as the internal reference. Data were presented as mean ± SD, n = 4. a P < 0.05 versus control; * P < 0.05 DHA versus EPA. One-way ANOVA followed by Student-Newman-Keuls (SNK) test and student’s t test. Con: control

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