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Table 2 Changes in lipids, lipoproteins and their ratios from the end of the stabilization diet (T0) to the end of the experimental treatment period (T1)

From: Effect of a short-term dietary supplementation with phytosterols, red yeast rice or both on lipid pattern in moderately hypercholesterolemic subjects: a three-arm, double-blind, randomized clinical trial

 

Phytosterols (Group 1; M: 8, F: 12)

P vs. baseline

Red Yeast Rice (Group 2; M: 11, F: 11)

P vs. baseline

Phytosterols + Red Yeast Rice (Group 3; M: 12, F: 11)

P vs. baseline

 

Mean

SD

 

Mean

SD

 

Mean

SD

 

Δ TC (mg/dl)

−5.4

15.2

0.127

−38.1*

16.7

<0.001

−44.2*

25.8

<0.001

Δ TG (mg/dl)

−0.8

59.0

0.938

−16.6

54.2

0.164

+4.8

34.3

0.536

Δ HDL-C (mg/dl)

+1.0

5.5

0.430

+2.2

5.7

0.076

+0.1

7.1

0.951

Δ LDL-C (mg/dl)

−6.6

15.7

0.075

−32.5*

12.5

<0.001

−45.2*°

20.2

<0.001

Δ TC/HDL-C

−0.2

0.5

0.109

−0.6*

−0.3

<0.001

−0.8*

0.6

<0.001

Δ LDL-C/HDL-C

−0.2

0.4

0.050

−0.5*

−0.3

<0.001

−0.9*°

0.5

<0.001

Δ Apo B100 (mg/dl)

−3.0

11.8

0.271

−14.2*

11.0

<0.001

−19.3*°

13.1

<0.001

Δ ApoA1 (mg/dl)

+2.6

17.7

0.513

+6.7

19.5

0.122

+1.7

20.7

0.718

Δ Apo B100/ApoAI

−0.03

0.07

0.095

−0.1*

0.07

<0.001

−0.1*

0.08

<0.001

  1. TC Total Cholesterol, TG Triglycerides, Apo Apolipoprotein
  2. *p < 0.05 Vs. Phytosterols (Group 1); ° p < 0.05 Vs. Red Yeast Rice (Group 2)