Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population

Table 2 Correlation between HOMA-IR and measured parameters

Potential	Total		Non-central obesity		Central obesity
metabolic factors	r	P	r	P	r	P
WC (cm)	0.329	<0.001	0.15	<0.001	0.169	<0.001
BMI (kg/m²)	0.404	<0.001	0.266	<0.001	0.302	<0.001
SBP (mmHg)	0.134	<0.001	0.047	<0.001	0.05	0.008
DBP (mmHg)	0.128	<0.001	0.047	0.001	0.078	<0.001
HbA1c (%)	0.131	<0.001	0.004	0.785	0.187	<0.001
TG (mmol/L)	0.327	<0.001	0.235	<0.001	0.294	<0.001
TC (mmol/L)	0.081	<0.001	0.013	0.33	0.027	0.148
LDL (mmol/L)	0.118	<0.001	0.053	<0.001	0.015	0.423
HDL (mmol/L)	−0.239	<0.001	−0.213	<0.001	−0.186	<0.001
ALT (U/L)	0.216	<0.001	0.125	<0.001	0.27	<0.001
AST (U/L)	−0.049	<0.001	−0.133	<0.001	0.013	0.499
ALT/AST	0.343	<0.001	0.284	<0.001	0.372	<0.001

WC waist circumference, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated hemoglobin, HOMA-IR homeostasis model assessment-insulin resistance, TG triglycerides, TC total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, ALT alanine aminotransferase, AST aspartate aminotransferase. The data were Spearman’s correlation coefficients

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