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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Ascorbic acid promotes 3T3-L1 cells adipogenesis by attenuating ERK signaling to upregulate the collagen VI

Fig. 6

The possible mechanism of AA2P promoting the adipogenesis of 3T3-L1 cells. AA2P enters the cells by active transport and plays two roles. First, AA2P promotes the assembly and secretion of collagen VI as the hydroxyl factor co-enzyme, and then down-regulates the phosphorylation of ERK1/2. Second, VC down regulates ERK1/2 phosphorylation directly by a certain mechanism

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