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Table 4 The association of vitamin D plus omega-3 fatty acids supplementation with pregnancy outcomes

From: The effects of vitamin D and omega-3 fatty acids co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in patients with gestational diabetes

 

Placebo group

(n = 30)

Vitamin D 2

(n = 30)

Omega-33

(n = 30)

Vitamin D+ omega-34

(n = 30)

P5

Cesarean section (%)

11 (36.7)

9 (30.0)

9 (30.0)

8 (26.7)

0.863†

Preterm delivery (%)

1 (3.3)

0 (0.0)

0 (0.0)

0 (0.0)

0.388†

Pre-eclampsia (%)

3 (10.0)

3 (10.0)

2 (6.7)

3 (10.0)

0.960†

Polyhydramnios (%)

2 (6.6)

2 (6.6)

2 (6.6)

2 (6.6)

>0.999†

Macrosomia > 4000 g (%)

5 (16.7)

2 (6.7)

3 (10.0)

2 (6.7)

0.525†

Gestational age (weeks)

39.1 ± 1.1

39.2 ± 1.0

39.0 ± 1.4

39.3 ± 0.9

0.658

Newborns’ weight (g)

3323.0 ± 407.1

3308.3 ± 604.0

3475.0 ± 395.2

3311.7 ± 502.2

0.480

Newborns’ length (cm)

50.4 ± 1.1

50.2 ± 3.0

51.3 ± 2.1

49.9 ± 2.7

0.103

Newborns’ head circumference (cm)

35.7 ± 1.3

35.9 ± 2.9

35.5 ± 1.4

35.3 ± 2.7

0.744

1- min Apgar score

8.8 ± 0.4

8.7 ± 0.4

8.7 ± 0.4

8.8 ± 0.4

0.779

5- min Apgar score

9.8 ± 0.4

9.7 ± 0.4

9.7 ± 0.4

9.8 ± 0.4

0.779

Newborns’ hyperbilirubinemia (%)

12 (40.0)

6 (20.0)

10 (33.3)

3 (10.0)

0.037†

Newborns’ hospitalization (%)

12 (40.0)

6 (20.0)

10 (33.3)

3 (10.0)

0.037†

Newborns’ hypoglycemia (%)

6 (20.0)

4 (13.3)

5 (16.7)

4 (13.3)

0.876†

  1. Values are means ± SDs for continuous measures and are number (%) for dichotomous variables
  2. †Obtained from Pearson Chi-square test
  3. 2Receiving 50,000 IU vitamin D every 2 weeks plus placebo for omega-3 fatty acids twice a day
  4. 3Receiving 1000 mg omega-3 fatty acids (180 mg EPA and 120 mg DHA) twice a day plus placebo for vitamin D every 2 weeks
  5. 4Receiving 50,000 IU vitamin D every 2 weeks plus 1000 mg omega-3 fatty acids twice a day
  6. 5Obtained from ANOVA test